Diagnostic Efficacy of Prenatal Color Doppler Ultrasonography in Patients with Congenital Cardiovascular Malformation

Liu, Yanfu; Li, Zheng; Zheng, Kangjie; Wang, Haijun; Li, Mingchun; Fan, Bo; Liu, Tianping; Li, Lijia; Dai, Mingliang

doi:10.1166/jmihi.2018.2529

Cited by 1 publication

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“…From the abstract, it appears that this study considered antenatal ultrasound techniques and autopsy in a loss in utero population. 249 It is unclear what, if any, effect inclusion of this study may have had on the findings of this systematic review. In addition to this, there were a number of seemingly applicable studies which could not be included due to the stringent inclusion and exclusion criteria laid out in this systematic review.…”

Section: Discussionmentioning

confidence: 97%

“…This was due to international interlibrary loans being unavailable during the COVID-19 pandemic. From the abstract, it appears that this study considered antenatal ultrasound techniques and autopsy in a loss in utero population 249. It is unclear what, if any, effect inclusion of this study may have had on the findings of this systematic review.…”

Section: Discussionmentioning

confidence: 99%

“…There was one article which was not retrievable for full-text screening and had to be excluded on that basis. 249 This was due to international interlibrary loans being unavailable during the COVID-19 pandemic. From the abstract, it appears that this study considered antenatal ultrasound techniques and autopsy in a loss in utero population.…”

Section: Discussionmentioning

confidence: 99%

“…Conference abstracts were included where there was enough information to extract data, adding weight to the findings and reducing publication bias. There was one article which was not retrievable for full-text screening and had to be excluded on that basis 249. This was due to international interlibrary loans being unavailable during the COVID-19 pandemic.…”

Section: Discussionmentioning

confidence: 99%

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Are non-invasive or minimally invasive autopsy techniques for detecting cause of death in prenates, neonates and infants accurate? A systematic review of diagnostic test accuracy

et al. 2023

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ObjectivesTo assess the diagnostic accuracy of non-invasive or minimally invasive autopsy techniques in deaths under 1 year of age.DesignThis is a systematic review of diagnostic test accuracy. The protocol is registered on PROSPERO.ParticipantsDeaths from conception to one adjusted year of age.Search methodsMEDLINE (Ovid), EMBASE (Ovid), CINAHL (EBSCO), the Cochrane Library, Scopus and grey literature sources were searched from inception to November 2021.Diagnostic testsNon-invasive or minimally invasive diagnostic tests as an alternative to traditional autopsy.Data collection and analysisStudies were included if participants were under one adjusted year of age, with index tests conducted prior to the reference standard.Data were extracted from eligible studies using piloted forms. Risk of bias was assessed using Quality Assessment of Diagnostic Accuracy Studies-2. A narrative synthesis was conducted following the Synthesis without Meta-Analysis guidelines. Vote counting was used to assess the direction of effect.Main outcome measuresDirection of effect was expressed as percentage of patients per study.FindingsWe included 54 direct evidence studies (68 articles/trials), encompassing 3268 cases and eight index tests. The direction of effect was positive for postmortem ultrasound and antenatal echography, although with varying levels of success. Conversely, the direction of effect was against virtual autopsy. For the remaining tests, the direction of effect was inconclusive.A further 134 indirect evidence studies (135 articles/trials) were included, encompassing 6242 perinatal cases. The addition of these results had minimal impact on the direct findings yet did reveal other techniques, which may be favourable alternatives to autopsy.Seven trial registrations were included but yielded no results.ConclusionsCurrent evidence is insufficient to make firm conclusions about the generalised use of non-invasive or minimally invasive autopsy techniques in relation to all perinatal population groups.PROSPERO registration numberCRD42021223254.

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Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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