2021
DOI: 10.3389/fimmu.2021.731876
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Diagnostic Model for Discrimination Between Tuberculous Meningitis and Bacterial Meningitis

Abstract: BackgroundThe differential diagnosis between tuberculous meningitis (TBM) and bacterial meningitis (BM) remains challenging in clinical practice. This study aimed to establish a diagnostic model that could accurately distinguish TBM from BM.MethodsPatients with TBM or BM were recruited between January 2017 and January 2021 at Tongji Hospital (Qiaokou cohort) and Sino-French New City Hospital (Caidian cohort). The detection for indicators involved in cerebrospinal fluid (CSF) and T-SPOT assay were performed sim… Show more

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Cited by 9 publications
(14 citation statements)
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References 42 publications
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“…We then assessed 65 full-text articles in detail ( Fig 1 ). Ultimately, 20 articles were selected for characteristic collection and data analysis (Tables 1 and 2 ) [ 28 47 ].…”
Section: Resultsmentioning
confidence: 99%
See 4 more Smart Citations
“…We then assessed 65 full-text articles in detail ( Fig 1 ). Ultimately, 20 articles were selected for characteristic collection and data analysis (Tables 1 and 2 ) [ 28 47 ].…”
Section: Resultsmentioning
confidence: 99%
“…The final dataset of 20 articles comprised 1,978 participants (701 TBM patients and 1,277 non-TBM individuals), with an overall TBM prevalence of 35.44%. Fourteen (70%) articles were reported from countries recognized as ‘high burden’ by the WHO [ 28 , 30 – 35 , 37 , 39 , 41 43 , 45 , 46 ]. Thirteen publications (65%) were of prospective studies [ 28 31 , 34 , 36 , 38 , 39 , 42 – 46 ].…”
Section: Resultsmentioning
confidence: 99%
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