Diagnostic performance of quantitative ultrasound calcaneus measurement in case finding for osteoporosis in Thai postmenopausal women

Abstract

Bone mass density measurement for predicting osteoporosis using QUS had a very low sensitivity and was not good enough to replace the standard tool (DXA).

The role of quantitative ultrasound in predicting osteoporosis defined by dual-energy X-ray absorptiometry in pre- and postmenopausal women

“…A large sample of routine clinical patients reflects everyday clinical practice and therefore might be more appropriate for the estimation of T score thresholds 47 . On the other hand, it is well known that there is a wide variety of reasons for patients' referral for bone status assessment.…”

Clinical Conformity Between Heel Ultrasound and Densitometry in Postmenopausal Women: A Systematic Review

“…In 4 out of the 15 papers included, the authors concluded that heel ultrasound cannot replace densitometry because of low conformity between the two methods . Sensitivity values of QUS compared with densitometry were 22 to 100% (mean 72.5 ± 20.8%) and specificity of 36.5 to 94% (65.4 ± 17.8%).…”

“…For cases in which the optimal T-score cutoff was calculated, the sensitivity and specificity are shown with respect to the optimal T-score value for diagnosis of In 4 out of the 15 papers included, the authors concluded that heel ultrasound cannot replace densitometry because of low conformity between the two methods. [16][17][18][19] Sensitivity values of QUS compared with densitometry were 22 to 100% (mean 72.5 6 20.8%) and specificity of 36.5 to 94% (65.4 6 17.8%).…”

“…In the next unfavorable paper, the sensitivity and specificity were calculated based on a standard T‐score, same as for DXA. However, after determining the optimal cutoff of the stiffness index as a value of 79.5 for osteoporosis, the sensitivity increased from 39.25 to 77.6% but the specificity fell from 91.71 to 59.6%.…”

Avaliação de parâmetros ultra-sônicos utilizados na caracterização de tecidos ósseos

“…Como método de traigem populacional tem sido feito por vários autores em diferentes países, dentre os quais citamos: Pluskiewicz (1999), que avaliou uma população polonesa de 740 mulheres (entre normais e com osteoporose) e 224 homens (entre normais e com osteoporose); Hadji (1999a), avaliou uma população de 1333 mulheres alemãs saudáveis com média de idade 50,5±11,5 anos; Kim (2000), avaliou uma população de 790 mulheres coreanas de idade entre 20 e 75 anos; Wehbe (2003), avaliou uma população de 4320 mulheres libanesas, para criar uma fonte de dados, de idade entre 20 e 79 anos e Panichkul (2004), avaliou uma população de 107 mulheres tailandesas com osteoporose para fazer comparação entre os parâmetros QUS e DXA.…”