Diagnostic Radiation in Pregnancy: Perception Versus True Risks

Cohen‐Kerem, Raanan; Nulman, Irena; Abramow-Newerly, Maria; Medina, D; Maze, Ronnen; Brent, Robert L.; Koren, Gideon

doi:10.1016/s1701-2163(16)32039-4

Cited by 21 publications

(17 citation statements)

References 23 publications

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“…It could also lead to delays in needed care for pregnant women. In one prospective study, 6 women (10% of Practice participants) exposed to low-dose diagnostic radiation during pregnancy chose to terminate the pregnancy, 4 stating that it was because of anxiety often caused by physician's advice. Educational interventions about radiation exposure should be considered to facilitate accurate risk estimation by physicians.…”

Section: Perceived Risk Of Radiationmentioning

confidence: 99%

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"Doctor, will that x-ray harm my unborn child?"

Ratnapalan¹,

Bentur²,

Koren³

2008

Canadian Medical Association Journal

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Section: Perceived Risk Of Radiationmentioning

confidence: 99%

“…These patients often question the potential effects of the radiation on the developing fetus, and they may perceive radiation as being very harmful. [1][2][3][4] A realistic and informed approach to counselling these patients can minimize the anxiety felt by both patients and health care providers.…”

mentioning

confidence: 99%

"Doctor, will that x-ray harm my unborn child?"

Ratnapalan¹,

Bentur²,

Koren³

2008

Canadian Medical Association Journal

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“…Such radiation exposure is still below the threshold dose for severe congenital malformation and should not, therefore, harm the fetus. 10 However, in many cases other types of examinations that are not associated with radiation, such as ultrasonography or magnetic resonance imaging (MRI), may provide the desired diagnostic information without measurably increasing the risk of fetal malformations.…”

mentioning

confidence: 99%

The treatment of Hodgkin's and non-Hodgkin's lymphoma in pregnancy

Pereg

Koren²,

Lishner³

2007

Haematologica

118

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Lymphoma is the fourth most frequent malignancy diagnosed during pregnancy, occurring in approximately 1:6000 of deliveries. Its occurrence may increase due to the current trend to postpone pregnancy until later in life and the suggested high incidence of AIDS-related non-Hodgkin's lymphoma in developing countries. The relatively rare occurrence of pregnancy-associated lymphoma precludes the conduction of large, prospective studies to examine diagnostic, management and outcome issues. Chemotherapy and radiotherapy during the first trimester are associated with increased risk of congenital malformations and this risk diminishes as pregnancy advances. In the vast majority of cases, when lymphoma is diagnosed during the first trimester, treatment with a standard chemotherapy regimen, following pregnancy termination should be recommended. In the rare patients at low risk, such as those with stage 1 Hodgkin's lymphoma or indolent non-Hodgkin's lymphoma, therapy can be delayed until the end of the first trimester and of embryogenesis while keeping the patients under close observation. When lymphoma is diagnosed during the second and third trimesters, evidence exists suggesting that full-dose chemotherapy can be administered safely without apparent increased risk of severe adverse fetal outcome.

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“…Нежелание проходить диагностические процедуры также было следствием отсутствия знания о различных типах радиационной экспозиции, пороговых эффектах и интерпретации экспериментальных данных относи-тельно их безопасности во время беременности [46]. Одним из возможных последствий переоценки риска использования ЛС во время беременности является отсутствие приверженности к лечению, когда почти семь из десяти женщин отказались от приема лекарств из-за боязни нежелательных эффектов на нерожденно-го ребенка.…”

Section: информационное обеспечение доказательности безопасного исполunclassified