Diagnostic yield of post-bronchoscopy sputum smear in pulmonary tuberculosis

Malekmohammad, Majid; Marjani, Majid; Tabarsi, Payam; Baghaei, Parvaneh; Sadr, Zahra; Naghan, Parisa Adimi; Mansouri, Davood; Masjedi, Mohammad Reza; Velayati, Ali Akbar

doi:10.3109/00365548.2012.643820

Cited by 4 publications

(5 citation statements)

References 18 publications

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“…This rate of detection was 40% by J.Balakrishna et al, [19] 60% by Saifquaiser et al [18] and 94% by S.Y.So et al [20] .Out of these 39 cases diagnosed, BAL was more effective method with sensitivity of 94.87%(CI of 82.68% to 99.37%) which was comparable to the study by de Gracia et al [21] where BAL had a sensitivity of 88% (15/17). Using post bronchoscopy sputum as the method of diagnosis, we were able to diagnose 23 patients with a sensitivity of 58.97% (CI of 42.1% to 74.43%) which was lesser than the study by K.Pipatvech et al [22] and M.Malekmohammad et al [17] where PBS had a sensitivity of 72% (13/18) and 76.7%(43/56) respectively.…”

Section: Discussioncontrasting

confidence: 68%

“…In our study, the BAL fluid smears were taken in all 72 cases and were positive for AFB in 30(41.66%) patients. In previous studies, it varied from 7.5% in S Charoenratanakul et al [16] to 57.1% in Malekmohammad M et al [17] BAL culture yielded M. tuberculosis in 51.38% patients in our study (37 cases out of 72) which was comparable to the 53% positivity (57 cases out of 108) by Choudhary S et al [15] In our study, Post bronchoscopy sputum were collected on 3 occasions and subjected to both smear for AFB and culture, yielding 25%(18/72) and 32% (23/72) positivity respectively. This was comparable to the 26% AFB smear positivity (13 cases out of 50) by Purohit et al [10] and 27.78%…”

Section: Discussionmentioning

confidence: 88%

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A Comparison of yield of bronchoalveolar lavage fluid examination versus post bronchoscopic sputum examination in the diagnosis of sputum smear negative pulmonary tuberculosis

Singh¹

2017

JMSCR

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Section: Discussioncontrasting

confidence: 68%

Section: Discussionmentioning

confidence: 88%

A Comparison of yield of bronchoalveolar lavage fluid examination versus post bronchoscopic sputum examination in the diagnosis of sputum smear negative pulmonary tuberculosis

Singh¹

2017

JMSCR

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“…The evaluation of sputum for acid fast bacilli in consequent days after bronchoscopy (PBS) proved to be an effective method for early diagnosis of TB [32]. In the present study, PBS was the main route for TB diagnosis in 4.5% of the patients with TB, while it was 12% and 7% in other studies [12,33], respectively, and the efficacy of PBS smears was not significantly related to HIV infection [32].…”

Section: Discussionmentioning

confidence: 41%

Clinical outcomes and complications of fiberoptic bronchoscopy in HIV-infected patients

Marjani¹,

Moinpour²,

Kiani³

et al. 2020

HIV & AIDS Review

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Introduction: Respiratory diseases, including infectious and non-infectious complications are common among patients with human immunodeficiency virus (HIV) infection. We aimed to determine the performance of fiberoptic bronchoscopy (FOB), bronchoalveolar lavage, and transbronchial lung biopsy in HIV-infected patients. Material and methods:The current retrospective study was performed in Masih Daneshvari Hospital, Tehran, Iran, from January 2003 to March 2017. Patients with HIV infection and 836 episodes of respiratory manifestations were selected. Indications, outcomes as well as results and complications of bronchoscopy were extracted. Performance of bronchoscopy to determine definite etiology and its ability to rule out other differential diagnoses were evaluated. Results:The indications of FOB were found in 289 subjects (34.6%) with respiratory diseases, of whom only 220 patients had undergone the procedure. Bronchoscopy confirming a final diagnosis was found in 87 (39.5%) patients and a diagnostic benefit was noted for minimum 66.7% of the subjects. Diagnostic ability of bronchoscopy was higher in patients suspected of pneumocystis jiroveci pneumonia (PJP), tuberculosis (TB), cytomegalovirus (CMV) pneumonitis, and in cases with ground-glass opacity and diffuse lung infiltrates (p-value: 0.003 and 0.035, respectively), and lower for subjects demonstrating reticulonodular infiltrations and right middle and lower lobes involvement (p-value: 0.008, 0.005, and 0.045, respectively). Procedure-related complications were reported in five subjects. Conclusions:FOB is a significantly advantageous and safe procedure in HIV-infected patients. Its diagnostic yield is higher in patients with ground-glass opacity and diffuse infiltration in chest computed tomography scan.

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“…Falls die Sputumdiagnostik keine wegweisenden Resultate ergibt, sollte eine Bronchoskopie mit gezielter Materialgewinnung erfolgen. Hier stellt die Entnahme einer zusätzlichen Sputumprobe nach der Untersuchung (postbronchoskopisches Sputum) eine wertvolle ergänzende diagnostische Möglichkeit dar 10 11 . Zur Häufigkeit der Untersuchung von Proben zur Verlaufskontrolle unter Therapie siehe Abb.…”

Section: Labordiagnostik Der Tuberkuloseunclassified

Tuberkulose im Erwachsenenalter

et al. 2022

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ZusammenfassungDie Tuberkulose ist in Deutschland eine seltene, überwiegend gut behandelbare Erkrankung. Weltweit ist sie eine der häufigsten Infektionserkrankungen mit ca. 10 Millionen Neuerkrankungen/Jahr. Auch bei einer niedrigen Inzidenz in Deutschland bleibt Tuberkulose insbesondere aufgrund der internationalen Entwicklungen und Migrationsbewegungen eine wichtige Differenzialdiagnose. In Deutschland besteht, aufgrund der niedrigen Prävalenz der Erkrankung und der damit verbundenen abnehmenden klinischen Erfahrung, ein Informationsbedarf zu allen Aspekten der Tuberkulose und ihrer Kontrolle. Diese Leitlinie umfasst die mikrobiologische Diagnostik, die Grundprinzipien der Standardtherapie, die Behandlung verschiedener Organmanifestationen, den Umgang mit typischen unerwünschten Arzneimittelwirkungen, die Besonderheiten in der Diagnostik und Therapie resistenter Tuberkulose sowie die Behandlung bei TB-HIV-Koinfektion. Sie geht darüber hinaus auf Versorgungsaspekte und gesetzliche Regelungen wie auch auf die Diagnosestellung und präventive Therapie einer latenten tuberkulösen Infektion ein. Es wird ausgeführt, wann es der Behandlung durch spezialisierte Zentren bedarf.Die Aktualisierung der S2k-Leitlinie „Tuberkulose im Erwachsenenalter“ soll allen in der Tuberkuloseversorgung Tätigen als Richtschnur für die Prävention, die Diagnose und die Therapie der Tuberkulose dienen und helfen, den heutigen Herausforderungen im Umgang mit Tuberkulose in Deutschland gewachsen zu sein.

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Diagnostic yield of post-bronchoscopy sputum smear in pulmonary tuberculosis

Cited by 4 publications

References 18 publications

A Comparison of yield of bronchoalveolar lavage fluid examination versus post bronchoscopic sputum examination in the diagnosis of sputum smear negative pulmonary tuberculosis

A Comparison of yield of bronchoalveolar lavage fluid examination versus post bronchoscopic sputum examination in the diagnosis of sputum smear negative pulmonary tuberculosis

Clinical outcomes and complications of fiberoptic bronchoscopy in HIV-infected patients

Tuberkulose im Erwachsenenalter

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