Diagnostic Yield Variation with Colonoscopy among Pediatric Endoscopists

Hochman, Jay; Figueroa, Janet; Duner, Emily; Lewis, Jeffery D.

doi:10.1159/000504837

Cited by 7 publications

(3 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In this study, the overall endoscopy diagnostic yield was 44.6%. Compared with the diagnostic yield of pediatric endoscopy involving different procedures, the yield for EGD was 39–63% [ 9 20 26 27 28 ] and the yield for colonoscopy was 33–75% [ 10 28 29 30 ] from related reports. If we categorized the diagnostic yield by endoscopic indication, the diagnostic yield varied from 20% among children with chronic abdominal pain to 85% among children with clinical GI bleeding.…”

Section: Discussionmentioning

confidence: 99%

Which Alarm Symptoms Are Associated With Abnormal Gastrointestinal Endoscopy Among Thai Children?

Wongteerasut

2024

Pediatr Gastroenterol Hepatol Nutr

View full text Add to dashboard Cite

Purpose Alarm symptoms (red flag signs) are crucial indications for management decisions on pediatric gastrointestinal endoscopy. We aimed to identify items in the alarm symptoms and pre-endoscopic investigations that predict abnormal endoscopy results. Methods A retrospective descriptive study was conducted among children aged under 18 years undergoing endoscopy. The patients were classified into normal and abnormal endoscopic groups. The incidence of alarm symptoms and pre-endoscopic investigations were compared between the groups. Univariate and multivariate logistic regression analyses were performed to determine independent risk factors for abnormal endoscopy. Results Of 148 participants, 66 were classified in the abnormal endoscopy group. Compared with the normal group, the abnormal group had a significantly higher prevalence of alarm symptoms. Moreover, hematemesis/hematochezia, anemia, low hemoglobin level, hypoalbuminemia, rising erythrocyte sedimentation rate, increased serum lipase, and blood urea nitrogen/creatinine ratio were significantly higher in the abnormal endoscopy group than in the normal group. Multivariate logistic regression analysis indicated that hematemesis/hematochezia and low hemoglobin level were independent risk factors for abnormal endoscopy. Conclusion The alarm symptoms and pre-endoscopic investigations were evaluated using predictive factors for abnormal pediatric endoscopic findings. According to multivariate logistic regression analysis, hematemesis/hematochezia and low hemoglobin levels were independent risk factors for abnormal endoscopy.

show abstract

Section: Discussionmentioning

confidence: 99%

Which Alarm Symptoms Are Associated With Abnormal Gastrointestinal Endoscopy Among Thai Children?

Wongteerasut

2024

Pediatr Gastroenterol Hepatol Nutr

View full text Add to dashboard Cite

show abstract

“…different ratio. The ratio was 1.6:1 from Bangladesh 23 , 2.1:1 from India 25 , 0.8:1 from USA 26 and 0.8:1 from Taiwan 3 . Different geographical distribution as well as variable genetic basis probably the causes.…”

Section: -5 H and E Stain Low-power Image Juvenile Rectal Polyp Varyi...mentioning

confidence: 93%

Spectrum of Colonoscopy in Children: A Tertiary Centre Experience from Bangladesh

Mahmud

Parvez

Baidya

et al. 2023

Dhaka Shishu (Child) Hosp. J.

View full text Add to dashboard Cite

Background: Pediatric colonoscopy is a safe, sensitive and crucial tool for diagnosing as well as treating children with lower gastrointestinal diseases. In resource-limited countries like Bangladesh, the practice of pediatric colonoscopy remains rudimentary, lacking in trained professionals and appropriate instrumentation. Objectives: The aim of the study was to find out the indications, common colonoscopic findings along with histopathologic evaluation and immediate post procedure complications of colonoscopy in children. Methods: This was a retrospective study; the records of all the patients whose age was less than 18 years and who underwent colonoscopy from January 2017 to December 2021 were studied. Results: Among the total of 196 children (8.23±4.12), the most common indications were lower gastrointestinal bleeding (LGIB) in 107 (54.6%) patients followed by chronic diarrhea in 33 (16.8%), recurrent abdominal pain (RAP) in 16 (8.2%), follow up Inflammatory bowel diseases (IBD) in 14 (7.1%), chronic constipation, weight loss, recurrent oral ulcer, intestinal tuberculosis (TB) and melena. The most common pathologic findings were polyps in 81 (61.4%) children followed by non-specific colitis in 19 (14.4%), IBD in 17 (12.9%) and infectious colitis in 09 (6.8%) cases. Minor adverse events occurred in only 2.0% of children. Conclusion: The commonest indication for pediatric colonoscopy was LGIB and the most common findings were colonic polyps. Pediatric colonoscopy is safe and effective diagnostic as well as therapeutic option for lower GI diseases. DS (Child) H J 2021; 38(1): 8-16

show abstract

“…Colonoscopies are considered more invasive than oesophagogastroduodenoscopies (OGDs); they require bowel preparation and longer anaesthetic time; they are performed less frequent than OGDs in most paediatric centres with the aim to investigate specific disorders, but a large proportion of paediatric colonoscopies were also reported as normal [11].…”

Section: Introductionmentioning

confidence: 99%

Clinical Utility of Paediatric Endoscopy and Correlation between Endoscopic and Histological Findings

et al. 2022

View full text Add to dashboard Cite

Background. The number of gastrointestinal endoscopies in children is rapidly increasing without evidence of a parallel increase in disease burden. The positive yield of paediatric endoscopies outside certain conditions is small but the impact of normal “negative” results on clinical management is poorly studied. Routine mucosal biopsy in all paediatric endoscopies is common practice. We aimed to assess the impact of normal endoscopy on patient care, defined by symptom improvement and discharge from hospital follow-up, and calculate the correlation between endoscopic and histological findings. Methods. Retrospective analysis of the first diagnostic endoscopy in children (2015–2019) from Evelina London Children’ Hospital, in London, UK. Endoscopy and histology findings were recorded. Symptoms and follow-up were reviewed up to six months after the endoscopy. Results. 362 children were included; 46.7% were female. Mean age 10.5 (±4.1) years, 66.3% underwent OGDs, and 33.7% underwent combined OGD and colonoscopies. 72.9% of endoscopies and 57.2% of all biopsies were normal. There was a strong positive correlation between endoscopic findings and biopsy results (phi 0.68 p < .001 ). 31.2% of children reported symptom improvement and were discharged from further follow-up after undergoing endoscopy after 1.9 (±1.5) clinics, phi 0.2 p < 0.001 between normal endoscopy and discharge. Conclusion. Negative endoscopy appears to influence clinical management and discharge from hospital follow-up in about a third of children undergoing endoscopy. The practice of routine biopsies in all paediatric endoscopies should be considered due to a strong positive correlation between normal endoscopies and normal biopsies.

show abstract

Diagnostic Yield Variation with Colonoscopy among Pediatric Endoscopists

Cited by 7 publications

References 23 publications

Which Alarm Symptoms Are Associated With Abnormal Gastrointestinal Endoscopy Among Thai Children?

Which Alarm Symptoms Are Associated With Abnormal Gastrointestinal Endoscopy Among Thai Children?

Spectrum of Colonoscopy in Children: A Tertiary Centre Experience from Bangladesh

Clinical Utility of Paediatric Endoscopy and Correlation between Endoscopic and Histological Findings

Contact Info

Product

Resources

About