Diastereomeric and enantiomeric selective accumulation of cypermethrin in the freshwater mussel Unio gibbus and its effects on biochemical parameters

Toxicity of pyrethroid cypermethrin on the freshwater snail Chilina parchappii: Lethal and sublethal effects

“…Between these two enzymes, CAT has been the most studied in invertebrates and one of the first enzymes proposed as an effective biomarker for oxidative stress (Sellami et al, 2015). It has been observed that CAT activity increases in the digestive gland of freshwater molluscs under CYP exposition (Arrighetti et al, 2018;Khazri et al 2015Khazri et al , 2016. However, CAT activity in C. parchappii was not altered in this study, probably because of the regulatory mechanism of ROS which may cause an increase, decrease or biphasic antioxidant enzymatic behaviour depending on toxic exposure conditions (Regoli and Giuliani, 2014).…”

“…However, despite its lower toxicity compared to other compounds, recent research reveals that pyrethroids like nerve impulse transmission. Besides, in the organs responsible for biotransformation reactions, the oxidative CYP metabolism may produce reactive oxygen species (ROS) that, if are not neutralised by the antioxidant defence system, induce oxidative stress (Khazri et al, 2016). These biological responses at the biochemical and physiological level are usually the first ones to appear and most sensitive ones.…”

“…Some parameters determined at the biochemical, physiological and histological level, could work as biomarkers since they are considered particularly valuable as early warning tools to monitor exposures to pollutants (Howcroft et al, 2009). Molluscs arouse great interest as model organisms when studying biomarkers of contamination due to their wide distribution, adaptability to different environmental conditions (Khazri et al, 2016) and high resistance to pesticides like CYP (Maund et al, 2012). Within molluscs, the gastropod Chilina parchappii is an abundant and representative species of the benthic assemblages of streams in the Pampas region in Argentina, an area that concentrates the largest agricultural activities of the country (Estebenet et al, 2002;Tietze and De Francesco, 2010).…”

A global synthesis of ecosystem services provided and disrupted by freshwater bivalve molluscs

“…Many of these records are based on the quantification of concentrations in mussel tissues and/or shells of, for example, heavy metals (Johns, 2001; Lukashev, 2008; Reis et al ., 2014; Labuschagne et al ., 2020), organic/chemical compounds (e.g. insecticides, pesticides, organotins, persistent organic compounds, organic halogens, polycyclic aromatic hydrocarbons, hormones) (Hayer, Wagner & Pihan, 1996; Regoli et al ., 2001; Richman & Somers, 2010; Khazri et al ., 2016; Bai & Acharya, 2019; Lécrivain et al ., 2020), microplastics (Su et al ., 2018) and radionuclides (Bollhöfer, 2012). In other studies, authors provide information about water quality by quantifying biomarkers that are proxies for physiological stress, including glutathione S‐transferase, glutathione reductase activity or DNA damage (de Lafontaine et al ., 2000; Binelli et al ., 2006; Contardo‐Jara & Wiegand, 2008; Michel et al ., 2013; Klimova et al ., 2017; Bonnail et al ., 2018; Bonnail, Macías & Osta, 2019 a ).…”

Assessment of carbamazepine acute toxicity in the cockle Cerastoderma edule through chemical, physiological and biochemical tools

“…The media was renewed every two days during the acclimatization with a continuous aeration. The exposure design was selected based on previous published studies (Khazri et al, 2016;Sellami et al, 2017). The laboratory temperature was maintained at 19 °C (field temperature) and the water temperature was maintained at 17 °C, and pH was 8.7 (Khazri et al, 2017).…”