Diastereoselective Fischer‐Type Pyrroloindole Synthesis and Its Application to the Synthesis of Chiral Pyrroloindole Alkaloids.

Abstract

Alkaloids U 0600 Diastereoselective Fischer-Type Pyrroloindole Synthesis and Its Application to the Synthesis of Chiral Pyrroloindole Alkaloids. -The facile preparation of optically active pyrroloindoles by diastereoselective Fischer-type pyrroloindole synthesis and short-step conversions of the cycloadducts to pyrroloindole alkaloids [cf. (XII), (XV)] are described. -(NISHIDA*, A.; USHIGOME, S.; SUGIMOTO, A.; ARAI, S.; Heterocycles 66 (2005) 181-185; Grad. Sch. Pharm. Sci., Chiba Univ., Inage, Chiba 263, Japan; Eng.) -H. Toeppel 21-192