Die Follikelpersistenz mit glandulärer Hyperplasie des Endometriums in klinischer und anatomischer Beziehung

Studies of Metropathia Haemorrhagica Cystica

“…11. c. have in general led to the conclusion that inultiparae occur in higher numbers than in a iiorinal material and that tlie pregnancies thus predispose to in. 11. c. (e. g. TIETZE, 1934). There are also, however, reports that do not corroborate this assumption, e. g. HBLUND'S (1944), this author having Sound the same difference for cases below as above 35 years as TIETZE, but his percentages for the whole inaterial are about the same a s in a comparison material from a medical clinic.…”

“…Distribution of cases by the relation the onset of symptoms bears to menarche proves the occurrence of a group in which the disease makes its appearance in direct connection with menarche (p. 53), i. e. during a period characterized by the bleeding5 being to a considerable extent physiologically anovular (v. MIKULICZ-RADECKI and KRAUSCH, 1935;NOVAK, 1947, and many others). A second and considerably higher frequency peak is found in the ages immediately preceding menopause (p. 54), hence once again during a period in which anovulation is a common phenomenon (TIETZE, 1934;NOVAK, 1945NOVAK, , 1946HAMBLEN, 1945, et d.). Besides these two anovulatoiy periods there occurs, as was shown earlier in this chapter, another one that has a similar physiological anovulation during the fertile age of the woman, viz.…”

“…authors have taken up for discussion the question of tlie ni. h. G. patient's age at menarche and found that on an average this age falls karlier than normally (e. g. GYLLENSVARD, 1931;TIETZE. 1934) or, as tlie case may be, later than normally (BECKMAN.…”

“…The bleeding typical of m. h. c. is always described as irregrrlar, acyclic (e. 9. TIETZE, 1934, et a!.). Usually the interval is prolonged, possibly to shorter or longer amenorrhoea1 periods, alternating with bleedings varying in duration and quantity.…”

“…A somewhat enlarged uterus was given by SCHRODER (1928) as a typical palpation find in m. h. c. He claimed that the consistency of the uterus may be soft in certain cases, but it is more commonly reported always to be firm (e. g . TIETZE, 1934). The reports on the size of the uterus are generally based on finds made at palpation, and RUNCE ( The increase in size may be caused by a thickening of the wall or by a distension of the cavity.…”