Die Porphyrinproduktion der Propioni-Bakterien in Abh�ngigkeit von externen Einfl�ssen

Fanta, D; Formanek, I; Poitschek, Ch.; Thurner, J

doi:10.1007/bf00412538

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Cited by 6 publications

(1 citation statement)

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“…We characterized the predominant porphyrin fraction secreted by P. acnes in vivo in inflammatory acne lesions. Coproporphyrin is the most important porphyrin produced and secreted extracellularly during cultivation of P. acnes 17–21 . We have now expanded the picture, showing that coproporphyrin III is also the main porphyrin fraction produced by P. acnes in vivo .…”

Section: Discussionmentioning

confidence: 66%

Induction of a chemoattractive proinflammatory cytokine response after stimulation of keratinocytes with Propionibacterium acnes and coproporphyrin III

Schaller

Loewenstein²,

Borelli³

et al. 2005

Br J Dermatol

100

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Section: Discussionmentioning

confidence: 66%

Induction of a chemoattractive proinflammatory cytokine response after stimulation of keratinocytes with Propionibacterium acnes and coproporphyrin III

Schaller

Loewenstein²,

Borelli³

et al. 2005

Br J Dermatol

100

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Porphyrin Photosensitization of Bacteria

Kjeldstad¹,

Christensen

Johnsson³

1985

Methods in Porphyrin Photosensitization

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A Novel Fluorimetric Method to Investigate Sebaceous Glands in Humans

Sauermann¹,

Herpens²,

Hoppe

et al. 1993

Noninvasive Methods for the Quantification of Skin Functions

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Propionibacteria are gram-positive anaerobic bacteria which inhabit the deeper parts of sebaceous follicles, normally low in oxygen. They produce porphyrins which are probably partially dispersed into the surrounding medium composed of sebaceous lipids and desquamating cells from the follicular wall [1]. Porphyrins are strongly fluorescent; their excitation maximum is located around 400 nm, emission bands are mainly in the range between 600 and 700 nm [2]. Illumination of the skin with light of the appropriate wavelength allows visualization of fluorescent glands within facial areas and the upper back [3] (Fig. 1). Assuming that fluorescence intensity and porphyrin content are related, which has been proven in the case of uptake of porphyrins by propionibacteria in culture [4], and knowing that fluorescence intensity is strongly related to the population density of at P. acnes the skin surface [5] and that comedones are densely populated with propionibacteria [6] , fluorescence intensity of individual glands could be a marker for comedonal content and for the comedogenic potential of

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Die Porphyrinproduktion der Propioni-Bakterien in Abh�ngigkeit von externen Einfl�ssen

Cited by 6 publications

References 8 publications

Induction of a chemoattractive proinflammatory cytokine response after stimulation of keratinocytes with Propionibacterium acnes and coproporphyrin III

Induction of a chemoattractive proinflammatory cytokine response after stimulation of keratinocytes with Propionibacterium acnes and coproporphyrin III

Porphyrin Photosensitization of Bacteria

A Novel Fluorimetric Method to Investigate Sebaceous Glands in Humans

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