“…Admittedly, depression of mitotic activity has been demonstrated in vitro, as has delay of proliferation of cells in tissue culture.20· 51,73 Heparin has not halted cell growth, however, in such experiments.73 Certain investigators have presented experimental evidence suggesting that there is interference with healing of skin wounds as a result of the effect of heparin or bishydroxycoumarin. 9 Dr. John H. Olwin, Chicago : I would like to discuss Dr. Warren's paper and congratulate him on a very nice study.…”