Dielectric modulated transparent gate thin film transistor for biosensing applications

Kumar, Ajay; Roy, Manan; Gupta, Neha; Tripathi, M. M.; Chaujar, Rishu

doi:10.1016/j.matpr.2020.01.453

Cited by 17 publications

(10 citation statements)

References 15 publications

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“…Biomolecules exist in different forms extending from nucleic acid, viruses, bacteria and proteins, and dimensions ranging from nm to μm. Knowledge of how these biomolecules function and their impact on several fields such as medicine, agriculture, and the food industry necessitated the early detection of biomolecules [ 29 , 30 , 31 , 32 , 33 , 34 ]. FET-based biosensors are realized by carving out a nanocavity at the source and/or drain end of the MOSFET.…”

Section: Applicationsmentioning

confidence: 99%

Improved Dielectrically Modulated Quad Gate Schottky Barrier MOSFET Biosensor

et al. 2023

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A novel Schottky barrier MOSFET with quad gate and with source engineering has been proposed in this work. A high-κ dielectric is used at the source side of the channel, while SiO2 is used at the drain side of the channel. To improve the carrier mobility, a SiGe pocket region is created at the source side of the channel. Physical and electrical characteristics of the proposed device are compared with conventional double gate Schottky barrier MOSFET. It has been observed that the proposed device exhibits better performance, with a higher ION/IOFF ratio and lower subthreshold slope. The high-κ dielectric, along with the SiGe pocket region, improves tunneling probability, while aluminum, along with SiO2 at the drain side, broadens the drain/channel Schottky barrier and reduces the hole tunneling probability, resulting in a reduced OFF-state current. Further, the proposed device is used as a biosensor to detect both the charged and neutral biomolecules. Biosensors are made by creating a nanocavity in the dielectric region near the source end of the channel to capture biomolecules. Biomolecules such as streptavidin, biotin, APTES, cellulose and DNA have unique dielectric constants, which modulates the electrical parameters of the device. Different electrical parameters, viz., the electric field, surface potential and drain current, are analyzed for each biomolecule. It has been observed that drain current increases with the dielectric constant of the biomolecules. Furthermore, the sensitivity and selectivity of the proposed biosensors is better than that of conventional biosensors made using double gate Schottky barrier MOSFETs. Sensitivity is almost twice that of a conventional sensor, while selectivity is six to twelve times higher than a conventional one.

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Section: Applicationsmentioning

confidence: 99%

Improved Dielectrically Modulated Quad Gate Schottky Barrier MOSFET Biosensor

et al. 2023

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“…Biosensors utilize chemical responses to distinguish the biochemical mixtures like antibodies, enzymes, nucleic acids, proteins, and so forth. So they are broadly utilized in numerous applications like checking of infections, food investigation, crime detection, ecological field observing, and for the investigation of biomolecules cooperation [ 1 , 2 ].…”

Section: Introductionmentioning

confidence: 99%

“…In the proposed DM-below-NCFET device (biosensor), the device’s channel limit gets improved with the electrical curve of biomolecules from which they can be distinguished. In the traditional MOSFET, the current through channel flow when the gate voltage transcends the threshold voltage ( ) [ 2 , 21 , 22 ]. With a general high doping concentration, the DM-below-NCFET acts as a resistor.…”

Section: Introductionmentioning

confidence: 99%

Detection of biomolecules in dielectric modulated double metal below ferroelectric layer FET with improved sensitivity

Pathak

Malhotra

Chaujar

2022

J Mater Sci: Mater Electron

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In this work, we examined the double metal below ferroelectric layer FET that is double metal below negative capacitance field-effect transistor (DM-below-NCFET) for biosensing application and change in nanocavity gap with biomolecules as protein, (cholesterol oxidase), streptavidin, and uricase. For measuring the electrical characteristic and neutral biosensing such as threshold voltage, switching ratio ( ) of the device which is higher than one without molecules by 1.52 times, sensitivity of protein enhanced by 1.11 over without biomolecule, limit of detection of protein is higher by 1.012 times over without molecule, shift in potential have been researched for cavity length 10 nm. The biosensor indicated improved sensitivity for biomolecules with the rise in their dielectric parameter. Moreover, modulation of the length of the gap of cavity was too examined, exposing that its increment (from 8 to 12 nm) altogether upgraded the sensitivity of the proposed biosensor. Visual TCAD (Technology Computer-Aided Design) software is used for simulating all results. In general, the consequences of this examination represent that such DM-below-NCFET biosensors can display extreme sensitivity (1.11) at small drain voltage (0.4 V), empowering their utilization for biosensor applications to analyze different infections which involve low power, extreme density, and enhanced speed.

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“…FETs were also recently utilized to diagnose the highly contagious COVID-19 illness due to the corona virus [4]. Various research groups [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16] have reported on the development of dielctrically modulated FET-based biosensors. Biosensors produced using FETs may be fabricated using either inorganic or organic semiconducting materials [17], [18].…”

Section: Introductionmentioning

confidence: 99%

Dielectric-Modulated Double Gate Bilayer Electrode Organic Thin Film Transistor-based Biosensor for Label-Free Detection: Simulation Study and Sensitivity Analysis

Jain¹,

Joshi²

2022

Preprint

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A dielectric-modulated double gate bilayer electrodes organic thin-film transistor (DMDGBE-OTFT) based sensor is proposed for label-free biomolecule detection. The double gate of DMDGBE-OTFT is used for creating two symmetrical gates underlap regions on both sides of the organic semiconductor. The parallel immobilization of biomolecule in two gates underlaps region changes the on-current (I ON ) of the DMDGBE-OTFT. Bilayer electrode is also used for significant reduction of barrier height to enhance the performance of the proposed device. The change in the drain current has been utilized to evaluate the sensitivity of the DMDGBE-OTFT for biomolecule recognition having different dielectric constants and corresponding charge densities using 2-D physics based numerical simulation when biomolecules are immobilized in the gate underlap area. The ATLAS TCAD tool is used to investigate the sensitivity performance of the DMDGBE-OTFT. The proposed DMDGBE-OTFT has 24.2% higher sensitivity in comparison to the recently reported OTFT-based biosensors for label-free detection of biomolecules. The DMDGBE-OTFT biosensor has a lot of potential for flexible biosensing applications in the future because of its flexibility , high sensitivity,biocompatibility and low cost.

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Dielectric modulated transparent gate thin film transistor for biosensing applications

Cited by 17 publications

References 15 publications

Improved Dielectrically Modulated Quad Gate Schottky Barrier MOSFET Biosensor

Improved Dielectrically Modulated Quad Gate Schottky Barrier MOSFET Biosensor

Detection of biomolecules in dielectric modulated double metal below ferroelectric layer FET with improved sensitivity

Dielectric-Modulated Double Gate Bilayer Electrode Organic Thin Film Transistor-based Biosensor for Label-Free Detection: Simulation Study and Sensitivity Analysis

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