Diet and Circadian Rhythms: Implications for Aging and Longevity

Editorial note for special issue on ‘dietary interventions for healthy ageing and longevity’

“…Reddy et al (2022) provide pre-clinical evidence that TRE regimen as a non-photic stimulus was effective to prevent age-related changes in the levels of serotonin and its related metabolites in the suprachiasmatic nuclei (SCN) and pineal gland of male Wistar rats and helped to restore synchronization of biological rhythms. The age-associated alterations in the neural and temporal organization of the principal biological pacemaker located in the SCN of the anterior hypothalamus results in circadian dysfunction (Jagota et al 2021) and adversely impacts several physiological functions and behavioral processes. Therefore, restricting the eating time window to 8-10 h during the day followed by about 14-16 h of fasting has been recently reported in several human pilot studies to promote metabolic health besides its ease of compliance in our day-to-day life.…”