Diet, fibers, and probiotics for irritable bowel syndrome

Galica, Adelina Nicoleta; Galica, Reitano; Dumitraşcu, Dan L.

doi:10.25122/jml-2022-0028

Cited by 21 publications

(22 citation statements)

References 55 publications

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“…Therefore, the increase in intestinal permeability could be caused by dyslipidemia, which increases zonulin levels and induces IBS. Fourth, diet has long been linked with IBS as a double-edged sword, it is a cause of diseases but also a treatment for symptom relief 37 . Some study suggested that gastrointestinal symptoms were frequently reported after intake of high-fat foods 38 – 40 , which can increase the level of plasma triglyceride 41 , 42 .…”

Section: Discussionmentioning

confidence: 99%

A Mendelian randomization study on the effects of plasma lipids on irritable bowel syndrome and functional dyspepsia

Xu,

Liu,

Tan

et al. 2024

Sci Rep

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Although functional gastrointestinal disorder (FGID) is a common clinical condition, its risk factors remain unclear. We performed a Mendelian randomization study to explore the association between plasma lipids and the risk of FGID. Instrumental variables closely related to six plasma lipids were obtained from the corresponding genome-wide association studies, and summary-level data on FGID, including irritable bowel syndrome (IBS) and functional dyspepsia (FD), were extracted from the FinnGen study. The primary inverse variance weighted method and other supplementary analyses were used to evaluate the causal relationship between diverse plasma lipids and FGID. For each increase in the standard deviation of triglyceride levels, there was a 12.0% increase in the risk of IBS rather than that of FD. Low- and high-density lipoprotein cholesterol, total cholesterol, apolipoprotein A, and apolipoprotein B levels were not associated with the risk of IBS or FD. Through this study, we identified the causal role of triglycerides in the pathogenesis of IBS, which could benefit further basic and clinical research.

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Section: Discussionmentioning

confidence: 99%

A Mendelian randomization study on the effects of plasma lipids on irritable bowel syndrome and functional dyspepsia

Xu,

Liu,

Tan

et al. 2024

Sci Rep

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“…Several psychological therapies are effective for IBS, yet none is better. The most substantial body of research supports the effectiveness of CBT-based therapies and gut-directed hypnosis over the long run [ 28 ]. There is a significant prevalence of psychological comorbidity in IBS.…”

Section: Reviewmentioning

confidence: 99%

Causative Factors, Clinical Manifestations, and Therapeutic Strategies for Irritable Bowel Syndrome

Anand,

Khatib

2024

Cureus

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Abdominal distress and irregular bowel movements are the hallmarks of irritable bowel syndrome (IBS), a chronic functional gastrointestinal illness (FGID). It is typified by recurring abdominal discomfort brought on by bowel movements or changes in pattern. Mind-body treatments have gained popularity recently as a way to manage IBS because of the role of the brain-gut axis. In addition to offering a helpful guide for identifying alternate diagnoses in patients exhibiting symptoms similar to IBS, this review attempts to offer an evidence-based solution to these perplexing problems. The etiology, diagnostic standards, and treatments for IBS will be summed up in this review, along with a summary of the available data supporting innovative digital medicines for these two illnesses. This brief study will give an overview of the pathophysiology, clinical characteristics, and treatment strategies of post-infectious irritable bowel syndrome (PI-IBS). In this study, we offer thorough methods for therapeutic therapy and talk about the possible contribution of psychological stress to pathophysiology. Additionally, to help with the introduction and suitability of these patient therapies, we offer a comprehensive review and meta-analysis of randomised controlled trials (RCTs) investigating the effectiveness of exclusion diets (low FODMAP and gluten-free diets, etc.) in IBS.

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“…Management of IBS includes three directions (Figure 1): pharmacological therapy (antidepressants, antispasmodics, and laxatives), interventions on hygienic-dietary revitalisation [41][42][43], and psychotherapy (cognitive behavioural psychotherapy, dynamic psychotherapy, hypnotherapy, and biofeedback-assisted stress management intervention) [10,26,44]. During the previous ten years, there has been an increase in interest in changing the lifestyle and the hygienic dietary regimen, with patients opting for one of the following diets: LFD, gluten-free diet, low-fibre diet, low-carb diet, ketogenic diet, and palaeolithic diet [22,45,46].…”

Section: Therapeutic and Nutritional Managementmentioning

confidence: 99%

“…It improves global symptoms, abdominal pain, bloating, bowel water content, and QoL [47][48][49][50]. During the previous ten years, there has been an increase in interest in changing the lifestyle and the hygienic dietary regimen, with patients opting for one of the following diets: LFD, gluten-free diet, low-fibre diet, low-carb diet, ketogenic diet, and palaeolithic diet [22,45,46].…”

Section: Therapeutic and Nutritional Managementmentioning

confidence: 99%

Effects of a Low-FODMAP Diet on Irritable Bowel Syndrome in Both Children and Adults—A Narrative Review

Morariu,

Avasilcai,

Vieriu

et al. 2023

Nutrients

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Irritable bowel syndrome is a typical gastrointestinal disease that causes bloating, flatulence, abdominal pain, diarrhoea, constipation, or alteration of the last two in adults and children. A diet low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAP) is one of the potential treatment strategies to reduce abdominal symptoms and increase the quality of life. The present narrative review aims to present a general overview of current studies that have evaluated the efficacy of a low-FODMAP diet against other diets in gastrointestinal symptoms, nutrient intake in adults and children, and lifestyle quality. The research was performed using seven searchable databases, which included the Cochrane Central Register of Controlled Trials (CENTRAL), Cochrane Database of Systematic Reviews (CDSR), Excerpta Medica Database (EMBASE), Medline, PubMed, Scopus, and Web of Science, up to March 2023. In conclusion, there is significant evidence that the follow-up of a low-FODMAP diet might be a feasible first-line therapeutic strategy to reduce stomach discomfort, pain, bloating, and quality of life for patients with irritable bowel syndrome.

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Diet, fibers, and probiotics for irritable bowel syndrome

Cited by 21 publications

References 55 publications

A Mendelian randomization study on the effects of plasma lipids on irritable bowel syndrome and functional dyspepsia

A Mendelian randomization study on the effects of plasma lipids on irritable bowel syndrome and functional dyspepsia

Causative Factors, Clinical Manifestations, and Therapeutic Strategies for Irritable Bowel Syndrome

Effects of a Low-FODMAP Diet on Irritable Bowel Syndrome in Both Children and Adults—A Narrative Review

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