2000
DOI: 10.1271/bbb.64.2588
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Dietary Effects of Eicosapentaenoic and Docosahexaenoic Acid Esters on Lipid Metabolism and Immune Parameters in Sprague-Dawley Rats

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Cited by 30 publications
(19 citation statements)
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“…Effect of dietary tocopherol and tocotrienol without fasting on their levels in various tissues of Sprague-Dawley rats. has also been reported that oral administration of the n-3 unsaturated fatty acids ␣-linolenic, eicosapentaenoic and docosahexaenoic acids decreases LTB 4 -releasing activity of rat PEC by decreasing arachidonic acid level in young Wistar (Matsuo et al, 2000) and SD rats (Hung et al, , 2000. In the present study, we showed that a significant decrease of LTB 4 -releasing activity of PEC isolated from aged SD rats fed ␣-Toc or T3 was induced without decreasing arachidonic acid level.…”
Section: Discussionsupporting
confidence: 75%
“…Effect of dietary tocopherol and tocotrienol without fasting on their levels in various tissues of Sprague-Dawley rats. has also been reported that oral administration of the n-3 unsaturated fatty acids ␣-linolenic, eicosapentaenoic and docosahexaenoic acids decreases LTB 4 -releasing activity of rat PEC by decreasing arachidonic acid level in young Wistar (Matsuo et al, 2000) and SD rats (Hung et al, , 2000. In the present study, we showed that a significant decrease of LTB 4 -releasing activity of PEC isolated from aged SD rats fed ␣-Toc or T3 was induced without decreasing arachidonic acid level.…”
Section: Discussionsupporting
confidence: 75%
“…Similarly DHA consumption, in the absence of EPA, does not inhibit many of the lymphocyte functions when total fat intake is low and held constant [22]. In contrast, studies with animal and human models using diets rich in fish oil or (n-3)PUFA, especially EPA and DHA, show that the dietary lipids are associated with suppression of T-cell proliferation [49][50][51][52]. T-cell proliferation is also suppressed in Atlantic salmon when the fish were fed a high (n-3)PUFA diet [3].…”
Section: Discussionmentioning
confidence: 99%
“…Dietary EPA supplementation in high-fat fed mice showed a higher accumulation of DHA in liver 29,45,46 . Shirouchi et al investigated the effect of n-3 PUFAs EPA,12.0 ; DHA, 28.1 containing PC on obesity-related disorders, which also showed that EPA and DHA levels were markedly increased by n-3 PUFAs-PC diet, compared with the egg-PC diet 47 .…”
Section: Fatty Acidmentioning
confidence: 96%