DietarySpirulina platensisalleviates aluminum and aluminum fluoride induced histopathological and biochemical alterations in mice kidney

Abstract

Aluminum and its salts widely used in our daily life have been reported nephrotoxic to humans and animals following prolonged exposure. Therefore the present study was made to examine the renoprotective role of Spirulina platensis against Al 3+ and AlF 3 in male Swiss albino mice. Exposure to these chemicals decreased feed and water intake, and body and kidney weights. Histology of kidney and their biochemistry were also markedly altered along with that of serum biochemistry. Spirulina not only minimize toxic effects of test chemicals but also favored faster recovery of treated mice after their withdrawal.