Dietary Inclusion of a Saccharomyces cerevisiae-Derived Postbiotic Is Associated with Lower Salmonella enterica Burden in Broiler Chickens on a Commercial Farm in Honduras

Abstract

Postbiotic feed additives may aid foodborne pathogen reduction during poultry rearing. The study objective was to evaluate a postbiotic additive in parallel to an industry control diet and the subsequent associated burden of Salmonella enterica on a single, commercial broiler farm in Honduras. Twelve houses were matched and assigned the standard diet (CON) or standard diet plus postbiotic (SCFP). New litter was placed in each house and retained across flock cycles with sampling prior to each chick placement and three consecutive rearing cycles. At ~33–34 days, 25 ceca were collected on-farm from each house, treatment, and cycle. Salmonella prevalence in litter for CON (30.6%) and SCFP (27.8%) were equivalent; however, Salmonella load within positive samples was lower (p = 0.04) for SCFP (3.81 log10 MPN/swab) compared to CON (5.53 log10 MPN/swab). Cecal prevalence of Salmonella was lower (p = 0.0006) in broilers fed SCFP (3.4%) compared to CON (12.2%). Salmonella load within positive ceca were numerically reduced (p = 0.121) by 1.45 log10 MPN/g for SCFP (2.41 log10 MPN/g) over CON (3.86 log10 MPN/g). Estimated burden was lower (p = 0.003) for SCFP flocks (3.80 log10 MPN) compared to CON (7.31 log10 MPN). These data demonstrate the preharvest intervention potential of postbiotics to reduce Salmonella enterica in broiler chickens.

Effect of a Bacillus subtilis plus Yeast Cell Wall Synbiotic on Salmonella Enteritidis Colonization in Ceca of Layer Pullets

“…BPQ, a synbiotic, consists of yeast cell wall MOS, 1,3/1,6 β-glucans (βG), and a selected Bacillus probiotic. Research has demonstrated that βG [37], MOS [23,38], and Bacillus probiotic [21] decrease SE colonization in chicken gut. Proposed modes of action for MOS, βG, and Bacillus probiotics, with relevance to Salmonella colonization, include acting as an alternative binding site for type-1 fimbria [39], upregulation of the immune system [40], and competitive exclusion [41,42], respectively.…”

Postbiotics: Functional Food Materials and Therapeutic Agents for Cancer, Diabetes, and Inflammatory Diseases

“…Postbiotics comprising Pediococcus acidilactici , Latilactobacillus sakei , and Staphylococcus xylosus flavonoids and phenolics have been shown to reduce Salmonella typhimurium in chicken drumsticks [ 217 ]. By consuming products made from the fermentation of Saccharomyces cerevisiae , it may be possible to limit the amount of Salmonella enterica contamination in poultry products by consuming products made from S. cerevisiae fermentation [ 218 ]. Postbiotic-containing preservatives were found to be as effective as frequently used commercial preservatives in preserving vacuum-packaged cooked sausages as natural preservation technologies [ 219 ].…”

Postbiotics: From emerging concept to application

“…Postbiotics containing flavonoids and phenolics from xylosus reduce the number of Salmonella typhimurium in chicken drumstick ( İncili et al, 2022). Dietary inclusion of Saccharomyces cerevisiae fermentation products may be a potential intervention to control Salmonella enterica in Poultry foods (Chaney et al, 2022). Postbiotic-containing preservatives were found to be equally effective as commonly used commercial preservatives in preserving vacuum-packaged cooked sausages, thus providing natural preservation technologies ( de Lima et al, 2022).…”