Dietary inulin affects the intestinal microbiota in sows and their suckling piglets

Paßlack, Nadine; Vahjen, Wilfried; Zentek, Jürgen

doi:10.1186/s12917-015-0351-7

Cited by 62 publications

(44 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Nevertheless, Lactobacillus CFU is higher at 24 hr of lactation ( p = .0340). These findings match with those of Paßlack, Vahjen, and Zentek (). The results obtained correspond to the normal colonization of the microbiota which is an important aspect as any alteration in the chronological development of the implantation of the microbiota will impact on the productive future of the animal (Bauer, Williams, Smidt, Verstegen, & Mosenthin, ; Buffie et al., ; Round & Mazmanian, ).…”

Section: Discussionsupporting

confidence: 91%

Fosfomycin residues in colostrum: Impact on morpho‐physiology and microbiology of suckling piglets

Paggi

Martínez

Dieguez

et al. 2018

Vet Pharm & Therapeutics

View full text Add to dashboard Cite

Fosfomycin is a broad-spectrum bactericidal antibiotic widely used in pig farms for the treatment of a wide variety of bacterial infections. In this study, the elimination of disodium fosfomycin in colostrum/milk of the sow and the impact of this antibiotic on the microbiota and intestinal morpho-physiology of suckling piglets were analyzed. The average amount of fosfomycin eliminated in colostrum (after administration of 15 mg/kg IM) during the first 10 hr postpartum was 0.85 μg/ml, and the mean residual amount ingested by the piglets was 0.26 mg/kg. The elimination profile of fosfomycin concentrations in colostrum occurs at a time of profound changes in the morpho-physiology of the gastrointestinal tract of the piglet. However, the studied concentrations did not produce imbalances on the microbiota or on the morpho-physiology of the gastrointestinal tract of the piglet. Concentrations of fosfomycin were maintained in the mammary gland above the MIC for more than 8 hr for pathogenic bacteria of productive importance. This would indicate that fosfomycin may be considered safe for the specific treatment of bacterial infectious processes in sows during the peri- and postpartum period. This first study with disodium fosfomycin stimulates awareness in the proper use of antimicrobials at farrowing.

show abstract

Section: Discussionsupporting

confidence: 91%

Fosfomycin residues in colostrum: Impact on morpho‐physiology and microbiology of suckling piglets

Paggi

Martínez

Dieguez

et al. 2018

Vet Pharm & Therapeutics

View full text Add to dashboard Cite

show abstract

“…No statistically signifi cant differences were found in other investigated faecal microorganisms (Table 4), except for the increase in the numbers of Enterococcus. Paßlack et al [2015] also showed that dietary inulin supplementation (3%) increased the numbers of enterococci, but it is contrary to other studies [Kleesen et al, 2007;Waitzberg et al, 2012].…”

Section: Results Of Medical Examinationcontrasting

confidence: 60%

“…But the results are controversial because of the differences in animal and human study models. Despite the variety of the data, it seems that inulin is likely to have a benefi cial impact on health status, especially in cases of infl ammation, infection and non-infectious diseases, during antibiotic and other drug consumption, constipation and other conditions when human intestinal microfl ora might be changed [Kleessen et al, 2007;Waitzberg et al, 2012;Paßlack et al, 2015].…”

Section: Introductionmentioning

confidence: 99%

An Inulin-Enriched Soy Drink and Its Lowering Effect of Oxidized Low Density Lipoproteins in Healthy Volunteers

Liutkevičius¹,

Speičienė²,

Vaičiulytė-Funk³

et al. 2016

Pol. J. Food Nutr. Sci.

View full text Add to dashboard Cite

Key words: drink, soy protein isolate, prebiotic dietary fi ber inulin, oxidized low density lipoproteins Due to selection of appropriate ingredients and parameters, a microbiologically-safe drink enriched with soy protein isolate (SPI) and prebiotic dietary fi ber inulin with high scores of acceptability was produced. The results of medical nutrition survey showed that on the 21 day of using drink the level of oxidized low density lipoproteins (LDL) signifi cantly decreased while the other biochemical parameters of blood of healthy patients as compared to the control tests remained unchanged. As well there was no apparent impact on the intestinal microfl ora balance of recipients established.

show abstract

“…This is especially relevant in swine production with each farm microbial environment being different and possibly impacting animal health status and the productive outcome. It has been shown that maternal diet or antibiotic treatment may induce a long lasting impact on the establishment of gut microbiota, gut biology and growth performances of offspring pigs [4–6]. However, none of these studies have associated the early-life fecal microbiota diversity and composition to the further suceptibility of post-weaning diarrhea in pigs.…”

Section: Introductionmentioning

confidence: 99%

Characterisation of Early-Life Fecal Microbiota in Susceptible and Healthy Pigs to Post-Weaning Diarrhoea

et al. 2017

View full text Add to dashboard Cite

Early-life microbial exposure is of particular importance to growth, immune system development and long-lasting health. Hence, early microbiota composition is a promising predictive biomarker for health and disease but still remains poorly characterized in regards to susceptibility to diarrhoea. In the present study, we aimed to assess if gut bacterial community diversity and composition during the suckling period were associated with differences in susceptibility of pigs to post-weaning diarrhoea. Twenty piglets from 5 sows (4 piglets / litter) were weaned in poor housing conditions to challenge their susceptibility to post-weaning diarrhoea. Two weeks after weaning, 13 pigs exhibited liquid faeces during 2 or 3 days and were defined as diarrhoeic (D) pigs. The other 7 pigs did not have diarrhea during the whole post-weaning experimental periodand were defined as healthy (H) pigs. Using a molecular characterisation of fecal microbiota with CE-SSCP fingerprint, Next Generation Sequencing and qPCR, we show that D and H pigs were mainly discriminated as early as postnatal day (PND) 7, i.e. 4 weeks before post-weaning diarrhoea occurence. At PND 7 H pigs displayed a lower evenness and a higher abundance of Prevotellaceae, Lachnospiraceae, Ruminocacaceae and Lactobacillaceae compared to D pigs. The sPLS regression method indicates that these bacterial families were strongly correlated to a higher Bacteroidetes abundance observed in PND 30 H pigs one week before diarrhoea. These results emphasize the potential of early microbiota diversity and composition as being an indicator of susceptibility to post-weaning diarrhoea. Furthermore, they support the health promoting strategies of pig herds through gut microbiota engineering.

show abstract

Dietary inulin affects the intestinal microbiota in sows and their suckling piglets

Cited by 62 publications

References 26 publications

Fosfomycin residues in colostrum: Impact on morpho‐physiology and microbiology of suckling piglets

Fosfomycin residues in colostrum: Impact on morpho‐physiology and microbiology of suckling piglets

An Inulin-Enriched Soy Drink and Its Lowering Effect of Oxidized Low Density Lipoproteins in Healthy Volunteers

Characterisation of Early-Life Fecal Microbiota in Susceptible and Healthy Pigs to Post-Weaning Diarrhoea

Contact Info

Product

Resources

About