Dietary supplementation with daidzein and Chinese herbs, independently and combined, improves laying performance, egg quality and plasma hormone levels of post-peak laying hens

Chinese herb ultrafine powder supplementation improves egg nutritional value and quality in laying hens

“…As nutritional supplements, Chinese herbs have been shown to boost laying performance, egg quality, plasma hormone levels (Zhang et al. 2021 ), eggshell strength, and anti-oxidative enzymes (Xiao et al. 2019 ) in poultry.…”

Dietary naringin supplementation on hepatic yolk precursors formation and antioxidant capacity of Three-Yellow breeder hens during the late laying period

“…Previous studies indicated that the yolk precursors formation in the liver is regulated by estrogen ( E 2 ), and may affect the egg production in hens ( Zhang et al, 2021a ). Further, the redox homeostasis of the liver is critical to yolk precursors formation ( Amevor et al, 2021 ).…”

Dimethylglycine Alleviates Metabolic Dysfunction-Associated Fatty Liver Disease by Improving the Circulating Estrogen Level via Gut Staphylococcus

“…Since the beginning of this century, the laying hen industry has been hoping to improve the laying rate of hens during the late laying period with the estrogenlike function of isoflavones. However, previous studies have shown that the isoflavones exert variable effects on increasing the estrogen level in laying hens, and the response dose of isoflavones for increasing the laying rate varies greatly between breeds and laying periods. , Furthermore, isoflavones increase eggshell thickness and may have adverse effects on the rate of offspring production and increase lipid deposition in the liver of laying hens. , Clinical studies in humans have revealed that despite the beneficial effects of endogenous estrogens, continued exposure to exogenous estrogens is a risk factor for the development of various cancers. − Therefore, alleviating fatty liver by exogenous supplementation of estrogen administration should be carefully considered. A methyl group donor can effectively prevent and alleviate fatty liver by regulating fat metabolism. − Supplementation with a methyl-group donor can improve the diversity and composition of gut microbiota, which reshapes the structure of gut microbiota in mice, tilapia, and cows .…”

“…However, previous studies have shown that the isoflavones exert variable effects on increasing the estrogen level in laying hens, and the response dose of isoflavones for increasing the laying rate varies greatly between breeds and laying periods. 19,20 Furthermore, isoflavones increase eggshell thickness and may have adverse effects on the rate of offspring production and increase lipid deposition in the liver of laying hens. 21,22 Clinical studies in humans have revealed that despite the beneficial effects of endogenous estrogens, continued exposure to exogenous estrogens is a risk factor for the development of various cancers.…”