Difference of corneal endothelial characteristics of diabetic and non‐diabetic cataract patients who underwent phacoemulsification at Dr Saiful Anwar hospital Malang

Abstract

Purpose: To compare the corneal endothelial characteristics of diabetic and nondiabetic cataract patients who underwent phacoemulsification. Methods: A retrospective study, data collected from medical records of patients who visited Cataract and Refractive Surgery Outpatient Clinic and underwent phacoemulsification at Saiful Anwar Hospital Malang, the tertiary hospital in East Java, Indonesia, between April 2021 to January 2022. Data collected regarding corneal endothelial condition were endothelial cell density (ECD), hexagonality and Coefficient variation (CV) examined using Specular Microscope (Nidek, CEM 530). Results: There were 32 eyes from 31 patients, consist of 55% men and 45% women, 17 eyes diabetic and 15 eyes non‐diabetic. The most common age range is 40–49 years old (35.5%). Baseline ECD and hexagonality were higher in diabetic compared to non‐diabetic patients (2781.35 ± 283 vs 2625.88 ± 389 and 67.71 ± 4 vs. 65.81 ± 4, respectively), while baseline CV was lower in diabetic patients (30.4 ± 4 vs. 33.2 ± 6) (p > 0.005). There was a decrease of ECD and hexagonality, but increase of CV after surgery in both groups (p > 0.005). Conclusions: There was significant decreased of ECD and Hexagonality but increased CV in diabetic group on pre phacoemulsification compared to post phacoemulsification. There are no statistically significant difference of baseline and endothelial damage between diabetic and non‐diabetic.