Background
Uninsured people who use drugs (PWUD) require extended parenteral antibiotic therapy when diagnosed with complex infections such as osteomyelitis. They are ineligible to enroll in our self-administered outpatient antimicrobial therapy (S-OPAT) program and instead sent to a skilled nursing facility (SNF). We aim to retrospectively assess clinical outcomes of PWUD discharged from our safety net hospital to complete OPAT in a SNF.
Methods
Using our hospital electronic medical record, PWUD and discharged to SNF for extended antibiotic therapy were identified for the study period 1/1/17 -4/30/18. Demographics, drug use, discharge diagnosis, antibiotic therapy, discharge disposition from SNF (AMA, early non-AMA, completed), 30-day emergency department (ED) utilization, and 30-day readmission were collected for the study cohort. ED-utilization and 30-day readmission rates were analyzed by disposition group.
Results
While the majority of patients completed treatment (83), a sizeable number left AMA (26) or early non-AMA (20) Patients who left early, AMA or non-AMA, had increased rates of 30-day readmission or ED-utilization (p=0.01), increased rates of 30-day readmission alone (p=0.01), but not ED-utilization alone (p=0.43) compared to patients who completed treatment.
Conclusions
In our cohort, many PWUD discharged to SNF to receive parenteral antibiotics do not complete treatment. These patients are observed to have increased healthcare utilization compared to patients completing therapy.