Differences in memory processes between inbred mouse strains C5BL/6J and DBA/2J.

Active- and passive-avoidance learning in inbred mice: Transfer of training effects

“…The results obtained in Phase I of this experiment are consistent with findings reported earlier (Sprott, 1972;Wimer et al, 1968). The performance of B6 mice was generally better than that of D2 mice, although the difference was small in the passive avoidance situation.…”

“…The apparatus used for passive avoidance testing was identical to that described by Wimer et al (1968), while the apparatus used for active avoidance testing was a slight modification of that described by Wimer. The conditioning chamber was a 15.3 x 15.9 x 16.6 cm clear Plexiglas box with a stainless steel grid floor.…”

ENU Mutagenesis Screening for Dominant Behavioral Mutations Based on Normal Control Data Obtained in Home-Cage Activity, Open-Field, and Passive Avoidance Tests

“…For PA performance, D2 mice were the worst learners among the groups at both shock intensities for males and at 0.3 mA for females, whereas B6 mice were the worst learners at 0.15 mA for females in this study. Some previous studies also indicate that D2 mice are poorer performers than B6 mice [1,29], although one study has indicated that the performance of B6 was poorer than that of D2 mice [18]. These inconsistent results for strains in the PA test may arise from differences in experimental conditions such as shock intensity [25].…”

Proactive and retroactive effects of diethyl ether on spatial discrimination learning in inbred mouse strains DBA/2J and C57BL/6J

“…For this strain, the EB Ss were clearly faster on Block 1 than the CB Ss. DISCUSSION Wimer (1968) and Wimer et al (1968) reported shorter passive avoidance and shock escape latencies for Strain C57BL/6J than for Strain DBA/ 2J when trials were presented at least 24 h apart. In the present experiment there were no differences in errors between the two strains, and swimming times were generally shorter 300 for the DBA/ 2J strain.…”

“…Es have reported either no effect of ether on learning (McGaugh, 1966) or a decremental effect (Abt, Essman, & Jarvik, 1961;Jarvik, 1964;Herz, Peeke, & Wyers, 1966;Pearlman, 1966;Alpern & Kimble, 1967). More recently, Wimer (1968) and Wimer, Symington, Farmer, & Schwartzkroin (1968) reported that ether administered immediately after learning trials actually facilitated shock escape and passive avoidance learning in the DBA/2J mouse strain, although it had no effect on the C57BL/6J strain. Cherkin (1968a) METHOD Ninety-six male 6-week-old mice of Strains DBA/2J and C57BL/6J served as Ss.…”