Differences in metabolic and inflammatory responses in lower and upper body high-intensity intermittent exercise

Lira, Fábio Santos; Panissa, Valéria Leme Gonçalves; Júlio, Ursula Ferreira; Franchini, Émerson

doi:10.1007/s00421-015-3127-7

Cited by 23 publications

(25 citation statements)

References 27 publications

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“…When the rate of glucose metabolism exceeds the oxidative capacity of the mitochondria (Dienel, 2013), lactate assists as a critical buffer, allowing glycolysis to rapidly produce significant amounts of energy. The higher variation in glucose after the HIIE1.25 compared to the HIIE2.5 may indicate that shorter HIIE stimulated glyconeogenesis (through an increase in catecholamines); however, as the exercise was very short, this glucose was probably not used during the exercise (Lira et al, 2015). On the other hand, the clearance of lactate during the recovery period was not measured, limiting a comparison between lactate levels after both HIIEs.…”

Section: Discussionmentioning

confidence: 99%

“…Lira et al (2015) submitted athletes to 4 sessions of the Wingate test at 100% of VO 2peak and observed an increase in IL-10 levels, inducing beneficial alterations in the resting inflammatory profile. Dorneles et al (2016) demonstrated that 10 × 60 s at 85–90% of maximal aerobic power, separated by 75-s at 50% of maximal aerobic power (which gives a mean workload of 65.6–67.8% of P max ), was able to induce a progressive elevation of IL-6 and IL-10 levels immediately and 30-min post exercise in both lean and overweight-obese subjects.…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, Cockcroft et al (2015) showed that a single bout of HIIE (8 × 1-min at 90% of the peak power, interspersed by 1.25 min recovery at 20 W) is an effective alternative to moderate intensity exercise to improve glucose tolerance, insulin sensitivity, and fat oxidation immediately after exercise. Studies have shown that high intensity intermittent exercise (HIIE) alone or combined with strength exercise promoted changes in metabolic and inflammatory responses (Meckel et al, 2009, 2011; Zwetsloot et al, 2014; Cabral-Santos et al, 2015; Lira et al, 2015; Wadley et al, 2016). To induce specific acute physiological responses an optimal ratio of intensity and duration of high intensity intervals and recovery as well as the resulting mean workload have to be optimized aiming for specific training adaptations (Tschakert and Hofmann, 2013).…”

Section: Introductionmentioning

confidence: 99%

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Inflammatory Cytokines and BDNF Response to High-Intensity Intermittent Exercise: Effect the Exercise Volume

Cabral-Santos¹,

Castrillón²,

Miranda³

et al. 2016

Front. Physiol.

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The purpose of this study was to compare the effects of two similar high-intensity intermittent exercises (HIIE) but different volume 1.25 km (HIIE1.25) and 2.5 km (HIIE2.5) on inflammatory and BDNF responses. Ten physically active male subjects (age 25.22 ± 1.74 years, body mass 78.98 ± 7.31 kg, height 1.78 ± 0.06 m, VO2peak 59.94 ± 9.38 ml·kg·min−1) performed an incremental treadmill exercise test and randomly completed two sessions of HIIE on a treadmill (1:1 min at vVO2max with passive recovery). Blood samples were collected at rest, immediately and 60-min after the exercise sessions. Serum was analyzed for glucose, lactate, IL-6, IL-10, and BDNF levels. Blood lactate concentrations was higher immediately post-exercise compared to rest (HIIE1.25: 1.69 ± 0.26–7.78 ± 2.09 mmol·L−1, and HIIE2.5: 1.89 ± 0.26–7.38 ± 2.57 mmol·L−1, p < 0.0001). Glucose concentrations did not present changes under the different conditions, however, levels were higher 60-min post-exercise than at rest only in the HIIE1.25 condition (rest: 76.80 ± 11.14–97.84 ± 24.87 mg·dL−1, p < 0.05). BDNF level increased immediately after exercise in both protocols (HIIE1.25: 9.71 ± 306–17.86 ± 8.59 ng.mL−1, and HIIE2.5: 11.83 ± 5.82–22.84 ± 10.30 ng.mL−1). Although both exercises increased IL-6, level percent between rest and immediately after exercise was higher in the HIIE2.5 than HIIE1.25 (30 and 10%; p = 0.014, respectively). Moreover, IL-10 levels percent increase between immediately and 60-min post-exercise was higher in HIIE2.5 than HIIE1.25 (37 and 10%; p = 0.012, respectively). In conclusion, both HIIE protocols with the same intensity were effective to increase BDNF and IL-6 levels immediately after exercise while only IL-10 response was related to the durantion of exercise indicanting the importance of this exercise prescription variable.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Inflammatory Cytokines and BDNF Response to High-Intensity Intermittent Exercise: Effect the Exercise Volume

Cabral-Santos¹,

Castrillón²,

Miranda³

et al. 2016

Front. Physiol.

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“…In addition to health benefits, intense exercise increases interleukin 6 (IL6) concentration by increasing its production in skeletal muscles, active in the regulation of energy supply in the muscles [18,27]. Moreover, higher expression of IL6 results in increased expression of the anti-inflammatory cytokine IL10.…”

Section: Discussionmentioning

confidence: 99%

Assessment of fatigue and the overtraining syndrome in female spinning instructors based on a survey and on the expression of selected genes

Bonisławska

Patyna

Wilczyński

et al. 2018

Balt J Health Phys Act

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“…It is important to consider that basketball Paralympic athletes and athletes competing in Judo and Wrestling, for example, normally execute repeated high-intensity actions during their competitive disputes. The understanding of the energy system dynamics during high-intensity interval exercise is important to improve the comprehension of the stimulus generated and, consequently, of the probable long-term adaptation to such effort (Lira et al, 2015). Thus, the main objective of this study was to investigate the performance and energy systems contribution during four upper-body Wingate tests interspersed by 3-min intervals.…”

Section: Introductionmentioning

confidence: 99%

Performance and energy systems contributions during upper-body sprint interval exercise

2016

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The main purpose of this study was to investigate the performance and energy systems contribution during four upper-body Wingate tests interspersed by 3-min intervals. Fourteen well-trained male adult Judo athletes voluntarily took part in the present study. These athletes were from state to national level, were in their competitive period, but not engaged in any weight loss procedure. Energy systems contributions were estimated using oxygen uptake and blood lactate measurements. The main results indicated that there was higher glycolytic contribution compared to oxidative (P<0.001) during bout 1, but lower glycolytic contribution was observed compared to the phosphagen system (adenosine triphosphate-creatine phosphate, ATP-PCr) contribution during bout 3 (P<0.001), lower glycolytic contribution compared to oxidative and ATP-PCr (P<0.001 for both comparisons) contributions during bout 4 and lower oxidative compared to ATP-PCr during bout 4 (P=0.040). For the energy system contribution across Wingate bouts, the ATP-PCr contribution during bout 1 was lower than that observed during bout 4 (P=0.005), and the glycolytic system presented higher percentage contribution in the first bout compared to the third and fourth bouts (P<0.001 for both comparisons), and higher percentage participation in the second compared to the fourth bout (P<0.001). These results suggest that absolute oxidative and ATP-PCr participations were kept constant across Wingate tests, but there was an increase in relative participation of ATP-PCr in bout 4 compared to bout 1, probably due to the partial phosphocreatine resynthesis during intervals and to the decreased glycolytic activity.

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Differences in metabolic and inflammatory responses in lower and upper body high-intensity intermittent exercise

Abstract: In conclusion, our results demonstrated that despite the higher performance in lower body HIIE, the inflammatory response did not differ between exercise modalities.

Cited by 23 publications

References 27 publications

Inflammatory Cytokines and BDNF Response to High-Intensity Intermittent Exercise: Effect the Exercise Volume

Inflammatory Cytokines and BDNF Response to High-Intensity Intermittent Exercise: Effect the Exercise Volume

Assessment of fatigue and the overtraining syndrome in female spinning instructors based on a survey and on the expression of selected genes

Performance and energy systems contributions during upper-body sprint interval exercise

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