Differences in the Antibiotic Resistance Pattern ofStaphylococcus aureusIsolated by Clinical Specimens in a University Hospital in South Korea

Abstract

Information on the prevalence of S. aureus and the current antimicrobial resistance profile is necessary in selecting the appropriate treatment of S. aureus infections in any part of the world. This study examined the frequency and antibiotic resistance list of S. aureus isolates obtained from clinical specimens at one hospital in Korea. A total of 1,746 gram positive cocci collected were identified as S. aureus. S. aureus isolates were obtained from different samples including sputum (N=565; 32.4%), endotracheal aspirate (358; 20.5%), wounds (329; 18.8%), blood (137; 7.8%), urine (67; 3.8%), and pus (59; 3.4%). All 1,545 S. aureus (100%) strains screened from sputum (565; 36.6%), endotracheal aspirate (388; 25.1%), wounds (329; 21.3%), blood (137; 8.9%), urine (67; 4.3%), and pus (59; 3.8%) were sensitive to glycopeptide (vancomycin, teicoplanin), oxazolidinone (linezolid) and stretogramin (quinupristin/dalfopristin). The prevalence of resistant S. aureus was significantly (P＜0.01) lower in urine, blood, pus, wounds, and sputum than in endotracheal aspirates. As a result, there was a significant difference in the antibiotic resistance of S. aureus according to the clinical specimens.

Description and Interrelationship Analysis of the Phenotypic and Genotypic Characteristics of MSSA and MRSA Strains Isolated From Healthcare Workers in North-eastern Brazil

“…31 Multidrug resistant bacteria are di cult to treat and treatment results are less effective than for susceptible bacteria. 32 Multidrug resistance was found in 72.41% of isolates in this study, principally to penicillin, erythromycin and azithromycin. In the same way, in a study of healthcare workers in a children's hospital in Iran, found high levels of resistance to these drugs.…”