Differences in the Phenolic Composition and Antioxidant Properties between Vitis coignetiae and Vitis vinifera Seeds Extracts

Weidner, Stanisław; Rybarczyk, Anna; Karamać, Magdalena; Król, Angelika; Mostek, Agnieszka; Grębosz, Joanna; Amarowicz, Ryszard

doi:10.3390/molecules18033410

Cited by 33 publications

(32 citation statements)

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“…The obtained values can be divided into 3 clusters: the first one including samples with tannin values between 0 mg g −1 and 10 mg g −1 (light grey bars); the second group with concentrations between 10 mg g −1 and 30 mg g −1 (dark grey bars); varieties with seeds presenting amounts of tannins greater than 30 mg g −1 (black bars). All these results were consistent with the data reported by Weidner et al 42 In general, the significant level variations of the phenolic concentrations observed in seeds and skins of different accessions could be strongly associated with various endogenous and exogenous factors, such as climate, berry size, grapevine genetics and nutrients. 40 In Tables 2-4 are reported the biochemical profiles of all the samples, as the amount of each secondary metabolite detected and investigated by LC-MS analysis.…”

Section: Food and Function Papersupporting

confidence: 93%

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Metabolic and biological profile of autochthonous Vitis vinifera L. ecotypes

et al. 2015

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Vitis vinifera L. is a plant species rich in phenolic compounds that are usually associated with the health benefits of wine and grape consumption in the diet. Anthocyanins, catechins, flavonol, phenolic acids and stilbenes are key molecular constituents of the Vitis berries, affecting the quality of grape products. The purpose of this work was to identify the metabolic profiles of 37 genetically certified V. vinifera Latial accessions. In particular, qualitative and quantitative analyses of specific secondary metabolites and total phenolic and tannin contents were performed by LC-MS and spectrophotometric analysis. In addition, since plant molecules are well-known for their free radical scavenging properties, the antioxidant effects of the sample extracts were evaluated through two different antiradical assays: DPPH and FRAP tests. Finally, a preliminary screening of the antiproliferative activity of each specimen on HCT-116 human colorectal cancer cells was conducted. All the results showed a great variety and amount of phenolic compounds in all accessions; moreover, we observed a significant correlation in the extracts between the metabolite concentration and bioactivity. Besides, some samples presented extraordinary biological effects, such as reduction of tumor cell growth not associated with cytotoxicity, supporting their use as possible future adjuvants for cancer therapy. In conclusion, the present research increased the scientific knowledge about Italian autochthonous vine ecotypes in order to valorize them and support their reintroduction in the local economic system.

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Section: Food and Function Papersupporting

confidence: 93%

“…42 A protein precipitation assay was used to determine the presence of both condensed and hydrolyzed tannins in seed sample extracts. The results, expressed as mg CE per g of SFW, are reported in Fig.…”

Section: Food and Function Papermentioning

confidence: 99%

Metabolic and biological profile of autochthonous Vitis vinifera L. ecotypes

et al. 2015

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“…The phytochemical analysis of red grape skin reveals the presence of phenolic compounds such as proanthocyanidins, ellagic acid, myricetin, quercetin, rutin, kaempferol, trans-resveratrol, cyanidin-3-glucoside, delphinidin-3-O-glucoside (myrtillin), petunidin-3-O-glucoside, peonidin-3-O-glucoside, malvidin-3-O-glucoside [39,40]. Furthermore, grape seeds are a rich source of polyphenols, which are characterized by a variety of properties, such as antibacterial and antioxidant activities [41,42]. Significant variations in the levels of total phenolic compounds, flavonoids, and anthocyanins in skins and seeds from different varieties of red grapes have previously been reported [41-43].…”

Section: Discussionmentioning

confidence: 99%

Inhibition of advanced glycation end products by red grape skin extract and its antioxidant activity

Jariyapamornkoon

Yibchok-anun

Adisakwattana

2013

BMC Complement Altern Med

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BackgroundThe objective of the present study was to determine the phytochemical content and the protective effect of red grape skin extract (RGSE) against fructose-mediated protein oxidation. In addition, RGSE was screened for its potential as an antioxidant using various in vitro models.MethodsAntioxidant activity was measured by 2,2-diphenyl-1-picrylhydrazyl (DPPH), hydroxyl radical scavenging activity, superoxide radical scavenging activity, trolox equivalent antioxidant capacity, ferric reducing antioxidant power (FRAP), ferrous ion chelating power. The total phenols content was measured by Folin–Ciocalteu assay, the flavonoids content by the AlCl3 colorimetric method. Antiglycation activity was determined using the formation of AGE fluorescence intensity, Nϵ-(carboxymethyl)lysine, and the level of fructosamine. The protein oxidation was examined using the level of protein carbonyl content and thiol group.ResultsThe results showed that the content of total phenolics, flavonoids and total anthocyanins in RGSE was 246.3 ± 0.9 mg gallic acid equivalent/g dried extract, 215.9 ± 1.3 mg catechin equivalent/g dried extract, and 36.7 ± 0.8 mg cyanidin-3-glucoside equivalent/g dried extract, respectively. In the DPPH radical scavenging activity, hydroxyl radical scavenging activity, and superoxide radical scavenging activity, RGSE had the IC50 values of 0.03 ± 0.01 mg/ml, 5.40 ± 0.01 mg/ml, and 0.58 ± 0.01 mg/ml, respectively. In addition, RGSE had trolox equivalent antioxidant capacity assay (395.65 ± 1.61 mg trolox equivalent/g dried extract), ferric reducing antioxidant power (114.24 ± 0.03 mM FeSO4/g dried extract), and ferrous ion chelating power (3,474.05 ± 5.55 mg EDTA/g dried extract), respectively. The results showed that RGSE at different concentrations (0.031–0.500 mg/ml) has significantly inhibited the formation of AGEs in terms of the fluorescence intensity of glycated BSA during 4 weeks of study. The RGSE markedly decreased the level of fructosamine, which is directly associated with the reduction of AGE formation and Nϵ-(carboxymethyl)lysine (CML). The results demonstrated the significant effect of RGSE on preventing protein oxidative damages, including effects on the thiol and protein carbonyl oxidation.ConclusionsThe present study revealed that RGSE would exert beneficial effects by virtue of its antioxidants and antiglycation. The findings could provide a new insight into the naturally occurring antiglycation properties of RGSE for preventing AGE-mediated diabetic complication.

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“…seeds, rose myrtle ( Rhodomyrtus tomentosa ), Mysore raspberry ( Rubus niveus ), white sorghum, or carrot (82, 86–88, 90, 118, 160–162). …”

Section: The Venus Flytrap (Dionaea Muscipula Solander Ex Ellis)mentioning

confidence: 99%

Venus Flytrap (Dionaea muscipula Solander ex Ellis) Contains Powerful Compounds that Prevent and Cure Cancer

Gaascht¹,

Dicato²,

Diederich³

2013

Front. Oncol.

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Chemoprevention uses natural or synthetic molecules without toxic effects to prevent and/or block emergence and development of diseases including cancer. Many of these natural molecules modulate mitogenic signals involved in cell survival, apoptosis, cell cycle regulation, angiogenesis, or on processes involved in the development of metastases occur naturally, especially in fruits and vegetables bur also in non-comestible plants. Carnivorous plants including the Venus flytrap (Dionaea muscipula Solander ex Ellis) are much less investigated, but appear to contain a wealth of potent bioactive secondary metabolites. Aim of this review is to give insight into molecular mechanisms triggered by compounds isolated from these interesting plants with either therapeutic or chemopreventive potential.

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Differences in the Phenolic Composition and Antioxidant Properties between Vitis coignetiae and Vitis vinifera Seeds Extracts

Cited by 33 publications

References 34 publications

Metabolic and biological profile of autochthonous Vitis vinifera L. ecotypes

Metabolic and biological profile of autochthonous Vitis vinifera L. ecotypes

Inhibition of advanced glycation end products by red grape skin extract and its antioxidant activity

Venus Flytrap (Dionaea muscipula Solander ex Ellis) Contains Powerful Compounds that Prevent and Cure Cancer

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