Different Clinical Characteristics AmongAeromonas hydrophila,Aeromonas veroniibiovar sobria andAeromonas caviaeMonomicrobial Bacteremia

Abstract

This study aimed to compare the clinical presentations of Aeromonas hydrophila, A. veronii biovar sobria and A. caviae monomicrobial bacteremia by a retrospective method at three hospitals in Taiwan during an 8-yr period. There were 87 patients with A. hydrophila bacteremia, 45 with A. veronii biovar sobria bacteremia and 22 with A. caviae bacteremia. Compared with A. hydrophila and A. veronii biovar sobria bacteremia, A. caviae bacteremia was more healthcare-associated (45 vs 30 and 16%; P = 0.031). The patients with A. caviae bacteremias were less likely to have liver cirrhosis (27 vs 62 and 64%; P = 0.007) and severe complications such as shock (9 vs 40 and 47%; P = 0.009) and thrombocytopenia (45 vs 67 and 87%; P = 0.002). The APACHE II score was the most important risk factor of Aeromonas bacteremia-associated mortalities. The APACHE II scores of A. caviae bacteremias were lower than A. hydrophila bacteremia and A. veronii biovar sobria bacteremia (7 vs 14 and 16 points; P = 0.002). In conclusion, the clinical presentation of A. caviae bacteremia was much different from A. hydrophila and A. veronii biovar sobria bacteremia. The severity and mortality of A. caviae bacteremia were lower than A. hydrophila or A. veronii biovar sobria bacteremia.

Virulence Diversity among Bacteremic Aeromonas Isolates: Ex Vivo, Animal, and Clinical Evidences

“…In the sepsis-related mortality rate of 9 cases of A. dhakensis bacteremia, 33.3%, were comparable with that of A. hydrophila bacteremia in the literature (33–36%) [5], [8], [9]. However, none of the 9 cases of bacteremia in our study died of sepsis due to A. hydrophila .…”

“…Of our 36 cases, only 33.3% had liver cirrhosis. In contrast, of 154 cases in another Taiwanese study, 64.3% had liver cirrhosis [5], and in a Japanese study 36.1% of 36 cases had chronic hepatic disease [25]. Moreover, in the two published studies, the accuracy of species identification based on traditional biochemical tests was questionable.…”

Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry Can Accurately Differentiate Aeromonas dhakensis from A. hydrophila, A. caviae, and A. veronii

“…have been associated with three species: Aeromonas hydrophila, A. veronii, and A. caviae (1)(2)(3)(4). Recently, increasing evidence has demonstrated that A. dhakensis is an important species, which might cause severe soft tissue and bloodstream infections (5,6).…”

Bacteremia por Aeromonas caviae en paciente con hepatitis autoinmune: presentación de caso

“…Estas se relacionan principalmente con casos de gastroenteritis, bacteriemia e infecciones de la vía biliar. Otras formas de infección menos usuales han sido reportadas, e incluyen infecciones pulmonares, meningitis, peritonitis y síndrome hemolítico urémico 16 . Este grupo de bacterias representa alrededor del 5% de los casos de bacteriemia en pacientes con cirrosis hepática 17 y una mortalidad entre el 30-50% en sepsis 16,18,19 , siendo mayor y más severa en aquellos infectados con A. hydrophila y A. veronii en comparación con A. caviae, donde se reporta una mortalidad entre el 5-17% de los casos 16,20 .…”