Differential diagnosis in hematochezia

Трухан, Д. И.; Тарасова, Л. В.; Бусалаева, Е. И.; Арямкина, О Л

doi:10.31146/1682-8658-ecg-175-3-87-93

Cited by 2 publications

(1 citation statement)

References 5 publications

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“…Вероятно, что в ближайшей перспективе показания к применению итоприда гидрохлорида будут расширены, так как получены экспериментальные данные о стимулирующем влиянии итоприда на моторику кишечника [38]. Представляется перспективным применение итоприда гидрохлорида у пациентов с хроническим дуоденитом и явлениями дуоденостаза [39].…”

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Priorities in choosing prokinetic for patients with functional dyspepsia: Focus on itopride

Babich

Зубарева

Ketova

2022

Medicinskij alfavit

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Functional dyspepsia is a widespread disease with many symptoms that reduce the patient's quality of life. The effectiveness of prokinetics, including in combination with proton pump inhibitors, has a high level of scientific evidence in the treatment of functional dyspepsia. The effectiveness of itopride hydrochloride is determined by a dual mechanism of action: antagonism to D 2-dopamine receptors and inhibition of acetylcholinesterase. The drug exceeds of metoclopramide and domperidone in safety in relation to cardiac and neurological disorders. Itopride hydrochloride is not expected to have pharmacokinetic interactions with other drugs metabolized by the CYP3A4 system. In addition to functional dyspepsia, itopride hydrochloride is indicated in the treatment of chronic gastritis, gastrointestinal symptoms associated with gastric dysmotility or delayed gastric emptying, such as bloating, rapid satiety, a feeling of fullness in the stomach after eating, pain or discomfort in the epigastric region, loss of appetite, heartburn, nausea and vomiting. The pharmacoeconomic analysis shows an advantage of Itopride-SZ in comparing of the direct cost of it with the original and several generic drugs. In this way, it allows recommend Itopride-SZ as an affordable drug for various cohorts of patients.

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Priorities in choosing prokinetic for patients with functional dyspepsia: Focus on itopride

Babich

Зубарева

Ketova

2022

Medicinskij alfavit

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Current views on the etiology, pathogenesis, diagnosis and treatment of Dieulafoy syndrome (review of literature)

Амарантов

Zarivchatsky

Aliyeva

et al. 2022

VESTNIK KHIRURGII IMENI I.I.GREKOVA

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The article is devoted to Dieulafoy syndrome, a rare pathology that manifests itself by intense bleeding from a defect of abnormally dilated vessels of the submucosal layer of the stomach. The article discusses the main methods of diagnosis, treatment and prevention of Dieulafoy syndrome, lists the synonyms of «Dieulafoy syndrome». A brief historical reference is given. The definition of the concept of «Dieulafoy syndrome» is given. The age and gender prevalence of this syndrome is analyzed. Variants of localization of the lesion in this syndrome are described. The main causes and risk factors for the occurrence of Dieulafoy syndrome are highlighted. The most common clinical manifestations are characterized. The advantages and disadvantages of various methods of diagnosis of Dieulafoy syndrome are described. Special attention is paid to the diagnosis and criteria for endoscopic verification of this syndrome. Various methods of treatment have been investigated: conservative, endoscopic and operative. The indications and contraindications to each of the treatment methods are described, as well as their advantages and disadvantages. Possible combinations of various methods of endoscopic hemostasis are listed. The question of choosing the optimal combination of different methods of endoscopic hemostasis is highlighted. Risk factors for recurrence of bleeding have been determined. The frequency of recurrence of bleeding in Dieulafoy syndrome was analyzed. A number of unresolved issues related to the diagnosis and treatment of this syndrome have been identified, such as issues of effective prevention and prediction of recurrent bleeding.

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Differential diagnosis in hematochezia

Cited by 2 publications

References 5 publications

Priorities in choosing prokinetic for patients with functional dyspepsia: Focus on itopride

Priorities in choosing prokinetic for patients with functional dyspepsia: Focus on itopride

Current views on the etiology, pathogenesis, diagnosis and treatment of Dieulafoy syndrome (review of literature)

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