The article demonstrates the results of a study to study the comparative assessment of the concentration of ammonia in the peripheral blood of patients with a viral infection of COVID-19 against the background of previously existing hepatic pathology and without it. There was a correlation between peripheral blood hyperammonemia and an increase in the concentration of markers of acute inflammation. The relationship between a high degree of hyperammonemia and a severe course / death as a result of the development of a new coronavirus infection in the studied patients was traced. The role of the initial chronic hepatic pathology (including non-alcoholic fatty liver disease) as a factor in the unfavorable course of the new coronavirus infection is highlighted.

The prevalence of nonalcoholic fatty liver disease (NAFLD) in the world steadily increasеs, turning it into a most prevalent liver disease in the last decade. NAFLD is a multidisciplinary problem, it attracts the attention of specialists of different specialities. Especially interesting is the clarification of the main links of the pathogenesis of nonalcoholic fatty liver disease, including the effect of endogenous microflora on the occurrence and course of disease. Modern information is represented in the review, it confirm the association between Helicobacter pylori infection (H. pylori) and NAFLD. It has been proven that successful eradication of H. pylori detaines the fibrosis in the liver, reduces the level of proinflammatory markers, and improves insulin resistance.

The appearance of hematohecia (blood in the bowel movement) is considered one of the most disturbing and serious symptoms of diseases of the gastrointestinal tract (GIT), signaling a violation of the integrity of the vessels of the intestine and mucous membrane. In the presented lecture the main diseases and conditions are considered, in the clinical picture of which the appearance of blood in the stool is noted, which must be considered in the course of differential diagnostics

No abstract