Differential diagnosis of retinal vasculitis

El‐Asrar, Ahmed M. Abu; Herbort, Carl P.; Tabbara, Khalid F.

doi:10.4103/0974-9233.58423

Cited by 65 publications

(10 citation statements)

References 92 publications

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“…Retinal vasculitis can be an isolated idiopathic condition; as of infectious diseases such as tuberculosis, Lyme disease, syphilis, toxoplasmosis, or acute retinal necrosis; as part of neurologic disorders such as multiple sclerosis; or in association with a systemic immune-mediated disease [12] . Active vascular disease is characterized by exudates around retinal vessels resulting in white sheathing or cuffing of the affected vessels, which may be segmental (skip lesions) or confluent.…”

Section: Discussionmentioning

confidence: 99%

A cross sectional study to clinically evaluate the retina of COVID-19 patients in a tertiary care Government designated COVID hospital

Gupta¹,

Gupta²

2023

Int. J. Med. Ophthalmol.

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Importance: Retinal vacuities can cause visual disturbances if not treated on time. Past researchers have shown an association of COVID19 with retinal vacuities. Objective: To evaluate the retina of patients who tested RTPCR or Rapid Antigen test positive for COVID-19.Design: Cross-sectional study Setting: COVID-designated Government tertiary healthcare institution. Clinical evaluation of the retina of the patients who suffered COVID-19, either hospitalized or home isolated and/ or who come for follow up in the medicine outdoor patient department was done from September 2020 to January 2022. Participants: 18 years of age and above were included in the study (by convenience sampling). Patients in the acute phase were evaluated cot side in COVID wards while the patients in the convalescent phase were those who were screened at least 15 days after hospital discharge and after 2 weeks of symptom onset or COVID testing in OPDs. Since the possibility of COVID-19 occurrence is high in diabetes and hypertension such patients were included in study to assess whether it can increase the frequency of retinal vasculitis Main Outcomes and Measures: Proportion of retinal vasculitis in patients of COVID-19. Results: Of the 274 study participants having COVID-19 who were evaluated for retinal changes, 187 were males and 87 were females; age group 40-60 years mainly: The patients of three different COVID-19 waves, having mild to severe disease and from acute or convalescent phase of disease were observed (including diabetic and hypertensive patients). None of the patients had significant retinal vasculitis changes in absence of systemic comorbidities. We observed one case of venous fullness, a case with superficial hemorrhage, and one having hard exudates where such retinal lesions were found without any systemic comorbidities.

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Section: Discussionmentioning

confidence: 99%

A cross sectional study to clinically evaluate the retina of COVID-19 patients in a tertiary care Government designated COVID hospital

Gupta¹,

Gupta²

2023

Int. J. Med. Ophthalmol.

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“…Retinal vasculitis may be associated with a number of systemic and local diseases. [ 8 , 9 ] It can be divided into infectious and noninfectious disorders described in Table 1 . [ 10 ]…”

Section: Discussionmentioning

confidence: 99%

Clinical study of profile of retinal detachment in vasculitis and its management at tertiary eye care hospital

Nagaraj,

Hiremath,

Tumbadi

et al. 2023

Indian Journal of Ophthalmology

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Purpose: The aim of the study was to understand the clinical profile and anatomical and visual outcome in Tractional/Combined (Tractional + Rhegmatogenous) Retinal Detachment due to vasculitis after surgical intervention. Methods: It was an interventional retrospective study of all cases who underwent surgery for RD with vasculitis at a single tertiary eye care center for over a period of 6 years. Patients with retinal detachment due to vasculitis were included in the study. All patients underwent the following surgical procedures: 240 belt buckle with three-port pars plana vitrectomy with membrane dissection and peeling with fluid gas exchange/with endolaser with silicon oil/C3 F8 gas injection. Results: In our study, 83.33% had preoperative vision of less than 6/60, whereas postoperatively 66.66% had vision of less than 6/60. Postoperatively 33.33% patients had vision better than 6/36. Of the six eyes operated for vasculitis with RD, retina was attached in five eyes following surgery. One patient had recurrent retinal detachment due to extensive proliferative vitreoretinopathy changes, and he was advised re-procedure but was lost for follow-up. The anatomical success was 83.33% on the first surgery. Conclusion: The overall anatomic success rate of retina reattachment surgery in vasculitis patient was good, and the visual outcome following the surgery can improve in majority of the cases. Hence, timely intervention is advocated.

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“…The diagnosis is confirmed by demonstrating leakage and blood vessel wall staining on fundus FA. Retinal vasculitis can be an isolated condition or a complication of local or systemic disorders, including infective, auto-immune, inflammatory, or neoplastic disorders [ 6 ].…”

Section: Discussionmentioning

confidence: 99%

Central retinal artery occlusion as a presenting symptom in Eales’ disease: a case report

et al. 2023

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Background Eales’ disease is an idiopathic peripheral retinal vasculopathy characterized by retinal phlebitis, ischemia, retinal neovascularization, and recurrent vitreous hemorrhages. But CRAO is an unusual presentation. Case presentation A 27-year-old healthy female nurse of Indian descent presented with sudden vision loss in her right eye upon awakening. Central retinal artery occlusion (CRAO), combined with mild central retinal vein occlusion (CRVO), was diagnosed. During the second of three consecutive sessions of hyperbaric oxygen treatments, her vision rapidly improved. One week later, she developed peripheral phlebitis in the same eye. Infectious, inflammatory, and hematologic etiologies were excluded. The systemic evaluation was normal except for a positive Mantoux tuberculin skin test. Following systemic steroidal treatment, she experienced gradual improvement of her vasculitis. Two weeks later, mild retinal phlebitis appeared in her left eye. Eales’ disease was diagnosed after the exclusion of other diseases. Conclusion This is an unusual Eales’ disease case, which presented as combined CRAO with mild CRVO. The association of CRAO and Eales’ disease is reported here for the first time, to our best knowledge.

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Differential diagnosis of retinal vasculitis

Cited by 65 publications

References 92 publications

A cross sectional study to clinically evaluate the retina of COVID-19 patients in a tertiary care Government designated COVID hospital

A cross sectional study to clinically evaluate the retina of COVID-19 patients in a tertiary care Government designated COVID hospital

Clinical study of profile of retinal detachment in vasculitis and its management at tertiary eye care hospital

Central retinal artery occlusion as a presenting symptom in Eales’ disease: a case report

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