2017
DOI: 10.1007/s12031-017-1001-2
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Differential Expression of Ion Channels in Adult and Neonatal Rat Ventral Respiratory Column

Abstract: In mammals, the neural control of breathing is attributed to circuits distributed along the ventral respiratory column (VRC) in the ventrolateral medulla. The VRC contains the kernel for generation of the inspiratory phase of respiratory rhythm and nuclei involved in central chemoreception. During development, the respiratory rhythm, as well as central chemosensitivity, adjusts to meet the changing physiological requirements associated with increased body weight and size. Gene expression in VRC ontogeny is wel… Show more

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Cited by 3 publications
(1 citation statement)
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“…González-Castillo et al [18] compared the changes in gene expression that occur in the ventral respiratory column of the ventrolateral medulla, which is involved in determining respiratory rhythm and central chemoreception, between adult and neonatal rats. Their analysis confirmed the differential expression of 84 genes involved in the expression of neuronal ion (K + , Na + , and Ca 2+ ) channels.…”
Section: Discussionmentioning
confidence: 99%
“…González-Castillo et al [18] compared the changes in gene expression that occur in the ventral respiratory column of the ventrolateral medulla, which is involved in determining respiratory rhythm and central chemoreception, between adult and neonatal rats. Their analysis confirmed the differential expression of 84 genes involved in the expression of neuronal ion (K + , Na + , and Ca 2+ ) channels.…”
Section: Discussionmentioning
confidence: 99%