Differential pulse polarographic studies of copper(II)-polyamine complexes at low ligand concentrations

Schmidt, Norman E.; Jiang, Pan; Philp, Robert H.

doi:10.1016/0022-0728(88)85131-3

Cited by 5 publications

(2 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…If the complexes were labile and since we have no excess of ligand, peak a should became broader with the increase of ligand concentration due to the reduction of two metal fractions, the noncomplexed and the one from the dissociation of the complex [30].…”

Section: Copper±bromazepam Complexmentioning

confidence: 99%

A Voltammetric Study of the Complexation of Copper by the Psychoactive Compounds 1,4-Benzodiazepines

2000

View full text Add to dashboard Cite

Complexation of copper ions with the 1,4-benzodiazepines bromazepam, midazolam and chlordiazepoxide is investigated using voltammetric methods, mainly differential pulse polarography in KNO 3 0.10 M and pH 7.0 + 0.1. Additional evidence of the complexation of copper was obtained by an UV-spectrophotometric study. Reduction of the metal ion as well as that of the ligands followed and the voltammetric behavior was interpreted in terms of complex formation. Stability constants have been determined for the experimental conditions used and the values were compared with those from the spectrophotometric study. The results show that copper(II) complexation is favored by the presence of chelating groups other than the azomethine group common to all the 1,4-benzodiazepines. It is also apparent that in some circumstances copper in the +1 oxidation state may be stabilized by complex formation. This result could only be inferred from the voltammetric data since in the presence of appropriate ligands the copper(I) oxidation state is produced electrochemically at the electrode/solution interface. The processes studied may help in understanding some of the features of the binding mechanisms between copper ion and the 1,4-benzodiazepine derivatives.

show abstract

Section: Copper±bromazepam Complexmentioning

confidence: 99%

A Voltammetric Study of the Complexation of Copper by the Psychoactive Compounds 1,4-Benzodiazepines

2000

View full text Add to dashboard Cite

show abstract

“…The variation in peak current upon ligand addition while E p remains constant and the nonexistence of any peak distortion indicate that the complexes formed are inert in the time scale of the electrochemical measurement (24,25); i.e., the complexes do not dissociate during measurement. In this situation, information regarding the complexation of copper in solution by the benzodiazepines can be extracted from the peak currents due to Cu(II) 3 Cu(0) reduction since, for inert systems, the intensity of the voltammetric signal is a direct measure of the metal ion concentration in solution not bound to the benzodiazepines, [Cu]Ј (25).…”

Section: Voltammetric Behaviormentioning

confidence: 99%

Copper–Psychoactive Drug Complexes: A Voltammetric Approach to Complexation by 1,4-Benzodiazepines

Santos¹,

Famila²,

Gonçalves³

2002

Analytical Biochemistry

View full text Add to dashboard Cite

Voltammetrische Untersuchung der Komplexbildung von Eisen(III) und Eisen(II) mit Iminodiacetat (IDA)

Meier¹,

Arrieta²,

Petrich³

et al. 1989

Zeitschrift anorg allge chemie

View full text Add to dashboard Cite

Die stufenweise Bildung der 1:1‐ und 1:2‐Komplexe von Eisen(III) und Eisen(II) mit dem dreizähnigen Chelatliganden IDA wird mittels Cyclovoltammetrie an einer stationären Platin‐Elektrode untersucht. Bei zunehmendem pH‐Wert und steigendem Konzentrationsverhältnis Ligand/Metallion aufgenommene Voltammogramme verdeutlichen die bevorzugte Komplexbildung von IDA mit FeIII und die vergleichsweise schwache Komplexbildung mit FeII. Die bisher unbekannte Bildungskonstante von FeIII(IDA)2− wird bestimmt. Weiterhin berichten wir über eine cis/trans‐Isomerie des Komplexes FeIII(IDA)2−.

show abstract

Differential pulse polarographic studies of copper(II)-polyamine complexes at low ligand concentrations

Cited by 5 publications

References 14 publications

A Voltammetric Study of the Complexation of Copper by the Psychoactive Compounds 1,4-Benzodiazepines

A Voltammetric Study of the Complexation of Copper by the Psychoactive Compounds 1,4-Benzodiazepines

Copper–Psychoactive Drug Complexes: A Voltammetric Approach to Complexation by 1,4-Benzodiazepines

Voltammetrische Untersuchung der Komplexbildung von Eisen(III) und Eisen(II) mit Iminodiacetat (IDA)

Contact Info

Product

Resources

About