Differentiation between Cerebral Embolism and Thrombosis on Sequential CT Scans

Thrombotic occlusion of the middle cerebral artery.

“…To improve the reliability of the selection of thrombotic MCA occlusion, patients who had atrial fibrillation or carotid artery ulceration were excluded based on clinical features, CT findings, and angiographic findings. 5 It has been reported frequently that embolic MCA occlusion is more common than thrombotic MCA occlusion 14 -23 -26 ; Lhermitte et al 15 found that only 12.5% of 40 MCA occlusions were due to local thrombosis. However, in the Japanese population thrombotic MCA occlusion is reported to be more common.…”

“…4 Thrombosis is usually thought to have a less-sudden onset, to be less severe clinically, and to have a computed tomographic (CT) image of an irregular low density area (LDA) without midline shift. 5 Embolic cerebral infarction as reported by the Harvard Cooperative Stroke Registry, 6 Blackwood et al, 7 and Jorgensen and Torvik 8 had an incidence of 37%, 48%, and 47%, respectively. Although many authors 9 " 13 have emphasized atherosclerotic thrombosis as the most common cause of cerebral infarction, accounting for 80-95%, some 1415 have found thrombotic etiology of MCA occlusion to be less frequent.…”

Passive Immunotherapies for Central Nervous System Disorders: Current Delivery Challenges and New Approaches

“…Ischemic strokes have the highest incidence among all cases of stroke and are caused due to obstruction of blood flow within cerebral vessels that may be attributed to one or more factors, e.g., fatty deposits along vessel walls that narrow the vessel lumen (atherosclerosis), elevated blood pressure, diabetes, and genetic predisposition. , The obstruction in the cerebral blood vessel may be caused either due to the formation of a blood clot (thrombus) within the brain itself (referred to as cerebral thrombosis) or a blood clot that migrates from the periphery into the brain (referred to as a cerebral embolism) . Arterial occlusion in stroke triggers a sequence of events leading to cell death and subsequent cognitive damage due to ischemia and neuroinflammatory responses in the brain .…”

Über die Erkennbarkeit frischer Großhirninfarkte im CT

“…The detectability of supratentonal brain infarctions therefore mainly depends on infarction type and size. The detection rate of territorial infarctions after [18], jedoch höher als in den meisten Serien [1,7,10,14,17,18,19]. Das HMCAS korrelierte deutlich mit der Infarktgroe und erwies sich somit als Voraussagezeichen eines groen lnfarkts mit schlechter Prognose [1,9,10,12,13,14,15,19,20].…”