Diffusion-weighted imaging (DWI) of adenomyosis and fibroids of the uterus

Jha, Reena; Zanello, Paulo A.; Ascher, Susan M.; Rajan, Sunder S.

doi:10.1007/s00261-014-0095-z

Cited by 20 publications

(17 citation statements)

References 34 publications

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“…Die Adenomyose des Uterus als nicht neoplastische, relativ häufige Erkrankung mit ektopem Endometrium innerhalb des Myometriums kann fokal oder diffus auftreten und weist eine niedrige bis mittlere Signalintensität im diffusionsgewichteten Bild auf. Die ADC-Werte lagen einer Studie zufolge unter denen des normalen Myometriums bei etwa 0,86 ± 0,30 × 10 -3 mm 2 /s [22]. Leiomyome als die häufigsten benignen Raumforderungen im Uterus können histologisch teils sehr komplex sein.…”

Section: Uterus Und Zervixunclassified

Diffusionsbildgebung: Technik und klinische Anwendung

Kukuk¹,

Greschus²,

Goldstein³

et al. 2017

Radiologie up2date

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Section: Uterus Und Zervixunclassified

Diffusionsbildgebung: Technik und klinische Anwendung

Kukuk¹,

Greschus²,

Goldstein³

et al. 2017

Radiologie up2date

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“…Both fibroid and adenomyosis are the most common benign condition of the uterus in women of reproductive age and often coexist with similar clinical complains (Jha et al ( 2014 ). On MRI, these two etiologies could be easily differentiated based on imaging signs and specific lesion characters (Takeuchi and Matsuzaki 2011 ).…”

Section: Resultsmentioning

confidence: 99%

Intravoxel incoherent motion diffusion-weighted imaging in differentiating uterine fibroid from focal adenomyosis: initial results

Tian

Zhang

et al. 2016

SpringerPlus

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To evaluate the performance of intravoxel incoherent motion (IVIM)-diffusion-weighted imaging (DWI) in differentiating uterine fibroids from focal adenomyosises. Twenty-five uterine fibroids and 21 focal adenomyosises prospectively underwent IVIM-DWI examination prior to surgery. Four parameters including apparent diffusion coefficient total values (ADCtot), true diffusion coefficient (D), pseudodiffusion coefficient (D*) and perfusion fraction (f) derived from IVIM-DWI images were separately calculated and compared across four groups. There was a statistically significant difference in IVIM-derived f parameter between fibroid and focal adenomyosis (p = 0.01) and control group (p = 0.02). Uterine fibroids gave higher coefficient of variation (CV) of all IVIM-derived parameters than focal adenomyosises. IVIM-DWI could improve the sensitivity and specificity of detecting focal adenomyosis to 100 and 92.6 %, respectively. IVIM-f parameter could be potentially used to better distinguish uterine fibroid from focal adenomyosis. The higher CV of IVIM-derived parameters with acceptable range is often observed in the diseased group.Electronic supplementary materialThe online version of this article (doi:10.1186/s40064-015-1635-x) contains supplementary material, which is available to authorized users.

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“…Some studies have examined the role of quantitative diffusion measurements for discerning adenomyosis from leiomyomas; however, these are, as yet, not currently employed in routine clinical practice. 28,29…”

Section: Magnetic Resonance Imaging Patient Preparation and Image Acqmentioning

confidence: 99%

Imaging Diagnosis of Adenomyosis

2020

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Uterine adenomyosis can be diagnosed on ultrasonography (US) and magnetic resonance imaging (MRI) with a high degree of accuracy. Adenomyosis is a myometrial process that can appear as diffuse or focal on imaging. Diffuse adenomyosis typically causes uterine enlargement, while focal adenomyosis can mimic other myometrial lesions, such as leiomyomas. Imaging features frequently seen on US include a heterogenous thickened myometrium and myometrial cysts. On MRI, widening of the junctional zone, whether focal or diffuse, and the presence of myometrial cysts, either simple or hemorrhagic, support the diagnosis of adenomyosis. Despite these characteristic imaging appearances, there are several gynecologic pathologies which can mimic adenomyosis and it is important to be vigilant of these when interpreting cross-sectional imaging exams. The decision to evaluate patients with US or MRI is contingent on multiple factors, including availability of the necessary technology and expertise for the latter. However, MRI appears to offer greater specificity and positive predictive value for the diagnosis of adenomyosis.

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Diffusion-weighted imaging (DWI) of adenomyosis and fibroids of the uterus

Abstract: The present study shows that ADC measurements have the potential to quantitatively differentiate between fibroids and adenomyosis.

Cited by 20 publications

References 34 publications

Diffusionsbildgebung: Technik und klinische Anwendung

Diffusionsbildgebung: Technik und klinische Anwendung

Intravoxel incoherent motion diffusion-weighted imaging in differentiating uterine fibroid from focal adenomyosis: initial results

Imaging Diagnosis of Adenomyosis

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