Diffusion‐weighted magnetic resonance imaging with apparent diffusion coefficient (ADC) determination in normal and pathological fetal kidneys

Chaumoître, Kathia; Colavolpe, N.; Shojai, R.; Sarran, A.; Ercole, C. D'; Panuel, M.

doi:10.1002/uog.3892

Cited by 44 publications

(36 citation statements)

References 16 publications

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“…In this study, it was shown that there is a negative correlation between the ADC-values with b-values of 700 and 800 s/ mm ² and the GA, which was significant for a b-value of 700 s/mm ² . This result is consistent with data of other studies [7,24,26], which indicates that the fetal kidney diffusion values are generally well reproducible. We suggest that an ADC may possibly serve as an indicator of the fetal renal function.…”

Section: Renal Imagingsupporting

confidence: 92%

“…The study of Chaumoitre et al [7] showed that of total 6 fetuses (3 fetuses with nephropathy and 3 fetuses with dilation of the urinary system) 4 fetuses had increased ADC-values with a b-value of 300 s/mm ² . In contrast, in another study of Savelli et al [25], the diffusivity in 15 fetuses with CAKUT was slightly lower than in fetuses with normal renal function (b-value of 700 s/mm 2 ).…”

Section: Renal Imagingmentioning

confidence: 99%

“…The other studies in which the fetal renal diffusivity was the subject of the study were performed with maximum b values of 700 s/mm² and minimum b values of 0, 50, 200 and 350 s/mm², respectively [7,[24][25][26]. With increasing b-value the signal-to-noise ratio in the image reduces and thereby the sensitivity to motion and to other artifacts increases [27,28].…”

Section: Renal Imagingmentioning

confidence: 99%

“…It not only determines some qualitative characteristics of the fetal kidney like the apparent diffusion coefficient (ADC) [7], but also provides a possibility for the determination of the AFV (AFVMRI). The study compared two methods of AF volumetry, and investigated the suitability of diffusionweighted imaging (DWI) of the fetal kidney to be used as a surrogate marker of fetal glomerular density in relation to the amount of AF.…”

Section: Introductionmentioning

confidence: 99%

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Comparison of amniotic fluid volumetry between fetal sonography and MRI - Correlation to MR diffusion parameters of the fetal kidney

Moschos¹,

Güllmar²,

Fiedler³

et al. 2017

Birth Defect

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Objective: Determine whether amniotic fluid volume (AFV) determination by magnetic resonance imaging (MRI) can be compared with ultrasound based amniotic fluid index (AFI) and whether diffusion weighted imaging (DWI) of the fetal kidneys can be used as surrogate marker for the assessment of AFV and fetal kidney function. Methods:In the period from August 2013 to September 2014 prospective evaluation of AFV based on TRUFI MRI in 2 spatial planes (AFVMRI) and ultrasound based AFI. Inclusion criteria for the evaluation were: 1) Full image of the fetus (including AF and placenta) in an MR-study in at least two planes (sagittal and coronal), 2) Layer thickness 8 mm, 3) DWI-images of the fetal kidney in two planes (sagittal and transverse to the fetus). ROI analysis of the ADC values in normal kidneys and in pathological fetal kidneys (CAKUT) as well as the correlation of AFVMRI vs. AFI, renal volume and ADC were performed. Results:The correlation between AFI (13.60 ± 2.46 cm) and AFVMRI (579 ± 353 mL) was 0.69 (p=0.03). There was no significant correlation between AFVMRI and kidney volume, between AFVMRI and ADC700 and ADC800. The B700-ADC values of fetuses with CAKUT (n=14) were considerably higher than the values in fetuses with healthy kidneys. Conclusion:Compared to AFI, AFVMRI showed higher accuracy, but was associated with higher time consumption. Thus it cannot be routinely recommended for the purpose of AFV-determination alone. MRI can be used to establish a relationship between kidney diffusion parameters, renal volume, GA and AFV in fetuses with CAKUT.

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Section: Renal Imagingsupporting

confidence: 92%

Section: Renal Imagingmentioning

confidence: 99%

Section: Renal Imagingmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Comparison of amniotic fluid volumetry between fetal sonography and MRI - Correlation to MR diffusion parameters of the fetal kidney

Moschos¹,

Güllmar²,

Fiedler³

et al. 2017

Birth Defect

View full text Add to dashboard Cite

show abstract

“…Chaumoitre analyzed the results of normal fetuses and of 10 fetuses affected by kidney pathology. In cases of renal polycystic disorders (both ARPKD and ADPKD), as in hydronephrosis, the images gave a hyperintensive signal [28].…”

Section: Discussionmentioning

confidence: 99%