BACKGROUND Dermatoglyphics refers to epidermal ridges that typically form under genetic control in the early stage of development. The aforesaid skin ridges are very likely to be influenced by various external, i.e. environmental circumstances in the course of the first trimester of pregnancy. In other words, it implies that the genetics message contained in the normal or abnormal genome is decoded throughout this particular period and likewise, reflected by dermatoglyphics. Dermatoglyphic pattern has been studied in various diseases. The main idea of this paper was to determine differences of fingerprints patterns in breast cancer patients and healthy women. METHODS The study was conducted on 50 histopathologically confirmed breast cancer women and 50 healthy women without family history of diagnosed breast cancer. The prints were analyzed by qualitative methods like arches, loops, whorls. The differences of qualitative dermatoglyphic patterns were tested for their significance using the Chi-square test and Fisher's exact test. A p-value of < 0.05 was considered statistically significant. RESULTS It was observed that six or more loops in the fingerprint pattern were statistically significant among the control group as compared to women with breast cancer. A pattern of six or more loops can be used as an indicator during calculation of the risk of the breast cancer. The difference between other parameters was not statistically significant. CONCLUSIONS It can be concluded in qualitative dermatoglyphic analysis that women with reduced number of digital loops tend to develop breast cancer. Therefore, the occurrence of breast cancer can be predicted and dermatoglyphics can be used as a non-invasive, anatomical marker and prediction tool to detect women with increased risk for breast cancer, who then can be subjected to timely mammography.