Qualitative Analysis of Digital Dermatoglyphics in a Small Patients Group in Bosnia and Herzegovina

Abstract

BACKGROUND Dermatoglyphics refers to epidermal ridges that typically form under genetic control in the early stage of development. The aforesaid skin ridges are very likely to be influenced by various external, i.e. environmental circumstances in the course of the first trimester of pregnancy. In other words, it implies that the genetics message contained in the normal or abnormal genome is decoded throughout this particular period and likewise, reflected by dermatoglyphics. Dermatoglyphic pattern has been studied in various diseases. The main idea of this paper was to determine differences of fingerprints patterns in breast cancer patients and healthy women. METHODS The study was conducted on 50 histopathologically confirmed breast cancer women and 50 healthy women without family history of diagnosed breast cancer. The prints were analyzed by qualitative methods like arches, loops, whorls. The differences of qualitative dermatoglyphic patterns were tested for their significance using the Chi-square test and Fisher's exact test. A p-value of < 0.05 was considered statistically significant. RESULTS It was observed that six or more loops in the fingerprint pattern were statistically significant among the control group as compared to women with breast cancer. A pattern of six or more loops can be used as an indicator during calculation of the risk of the breast cancer. The difference between other parameters was not statistically significant. CONCLUSIONS It can be concluded in qualitative dermatoglyphic analysis that women with reduced number of digital loops tend to develop breast cancer. Therefore, the occurrence of breast cancer can be predicted and dermatoglyphics can be used as a non-invasive, anatomical marker and prediction tool to detect women with increased risk for breast cancer, who then can be subjected to timely mammography.

Dermatoglyphy in Breast Cancer Patients: A Systematic Review

“…Of these, 48 studies were not suitable for further analysis because it is a duplicate (n = 16), the title filter is not A total of 21 articles met the criteria for review in this study. Of the 21 studies, 15 were conducted in India 13,14,[16][17][18][20][21][22][25][26][27][28][29]32,33 , 2 in Bulgaria 15,19 , 3 in Bosnia-Herzegovina 23,24,30 , and 1 in Egypt 31 . Several studies were included in the study and according to the selected criteria examined qualitative data on the relationship between breast cancer and whorl patterns as many as 14 studies 4,16,18,20,[21][22][23][25][26][27][28][30][31][32] .…”

“…Several studies were included in the study and according to the selected criteria examined qualitative data on the relationship between breast cancer and whorl patterns as many as 14 studies 4,16,18,20,[21][22][23][25][26][27][28][30][31][32] . Breast cancer and radial loop pattern were 9 studies 14,16,[21][22][23]25,26,31,32 . The following relates to the ulnar loop pattern as many as 9 studies 14,16,[21][22][23]25,26,[30][31][32] .…”

“…Breast cancer and radial loop pattern were 9 studies 14,16,[21][22][23]25,26,31,32 . The following relates to the ulnar loop pattern as many as 9 studies 14,16,[21][22][23]25,26,[30][31][32] .…”

“…Furthermore, the association between breast cancer and arch patterns was 14 studies 14,16,18,20,[21][22][23][25][26][27][28][30][31][32] . Breast cancer and the combination of ulnar and radial loop patterns were 5 studies 18,20,27,28,30 .…”

“…Paranjape (2015),Musanovic (2019),Raizada (2013), andAbdelhamid (2020) reported that the radial loop pattern was found to be less in the breast cancer group than the control group.The same thing was found in the ulnar loop fingerprint pattern in Fulari (2012), Paranjape (2015) and Musanovic (2019), and arch in Sakore (2016), Sridevi (2010) and Abdelhamid (2020) with p-value <0.05 and a good bias rating >50%. Meanwhile, there is no definitive conclusion regarding the differences in the combination of the ulnar+radial loop pattern in the case and control groups.Another significant dermatoglyphic parameter found in the breast cancer group was the ATD angle.…”