Digital light processing (DLP) of nano biphasic calcium phosphate bioceramic for making bone tissue engineering scaffolds

“…4,147,173 There are some methods to lessen anisotropic shrinkage, such as adjusting the ceramic slurry ratio to prevent the sedimentation of ceramic particles, 162 adding reinforcement materials, 169 optimizing the content of acrylate monomers to increase ceramic yield and decrease pyrolysis, 174 optimizing printing parameters to control interlayer pores, 175 and optimizing the sintering process. 176 Some studies have suggested compensating for shrinkage by adjusting the geometry model size, 169,177 but given the structural complexity of porous bone scaffolds, this approach is not always successful. 178…”

Section: Debinding and Sintering Processmentioning

confidence: 99%

“…The particle size of ceramics, the composition of slurry, printing, and heat treatment process all affect the mechanical strength of the scaffold. For UV-curable ceramic slurry, the solid loading is always emphasized as high as possible within the allowed range of printing viscosity to reduce weight loss during debinding, 86 which can be achieved by adding dispersant, 176 optimizing photosensitive resin composition and particle size distribution. 183 Li et al 184 reported that increasing the solid loading of HA/TCP slurry from 20 to 40 wt % increased the compressive strength by 5 times.…”

Section: Performance Of Vp-printed Bioactive Ceramic Bone Scaffoldsmentioning

confidence: 99%

Comprehensive Review on Fabricating Bioactive Ceramic Bone Scaffold Using Vat Photopolymerization

Liu

Wang

Liu³

et al. 2023

ACS Biomater. Sci. Eng.

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In recent years, bioactive ceramic bone scaffolds have drawn remarkable attention as an alternative method for treating and repairing bone defects. Vat photopolymerization (VP) is a promising additive manufacturing (AM) technique that enables the efficient and accurate fabrication of bioactive ceramic bone scaffolds. This review systematically reviews the research progress of VP-printed bioactive ceramic bone scaffolds. First, a summary and comparison of commonly used bioactive ceramics and different VP techniques are provided. This is followed by a detailed introduction to the preparation of ceramic suspensions and optimization of printing and heat treatment processes. The mechanical strength and biological performance of the VP-printed bioactive ceramic scaffolds are then discussed. Finally, current challenges and future research directions in this field are highlighted.

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“…80 The 50:50 β-TCP/Hap composite scaffold, after being sintered at a temperature of 1300 °C, obtained a compressive strength of 20.07 MPa and hardness of 6.36 GPa for 56.3% porosity. 81 82 The α-TCP is a reactive material that readily undergoes hydrolysis in an aqueous medium. Owing to its excellent resorbability, it finds its application in bone regeneration.…”

Section: Tricalcium Phosphatesmentioning

confidence: 99%

“…The 3-stage sintering of β-TCP from 1100 to 1300 °C resulted in a coarse interconnected microporous structure . The 50:50 β-TCP/Hap composite scaffold, after being sintered at a temperature of 1300 °C, obtained a compressive strength of 20.07 MPa and hardness of 6.36 GPa for 56.3% porosity . A study by Liu et al established the role of sintering aid in enhancing the mechanical property of the SLS-printed structures.…”

Section: Physical and Mechanical Characteristics Of Additive Manufact...mentioning

confidence: 99%

Review of Physical, Mechanical, and Biological Characteristics of 3D-Printed Bioceramic Scaffolds for Bone Tissue Engineering Applications

Thangavel

Elsen

2022

ACS Biomater. Sci. Eng.

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This review focuses on the advancements in additive manufacturing techniques that are utilized for fabricating bioceramic scaffolds and their characterizations leading to bone tissue regeneration. Bioscaffolds are made by mimicking the human bone structure, material composition, and properties. Calcium phosphate apatite materials are the most commonly used scaffold materials as they closely resemble live bone in their inorganic composition. The functionally graded scaffolds are fabricated by utilizing the right choice of the 3D printing method and material combinations to achieve the requirement of the bioscaffold. To tailor the physical, mechanical, and biological properties of the scaffold, certain materials are reinforced, doped, or coated to incorporate the functionality. The biomechanical loading conditions that involve flexion, torsion, and tension exerted on the implanted scaffold are discussed. The finite element analysis (FEA) technique is used to investigate the mechanical property of the scaffold before fabrication. This helps in reducing the actual number of samples used for testing. The FEA simulated results and the experimental result are compared. This review also highlights some of the challenges associated while processing the scaffold such as shrinkage, mechanical instability, cytotoxicity, and printability. In the end, the new materials that are evolved for tissue engineering applications are compiled and discussed.

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Digital light processing (DLP) of nano biphasic calcium phosphate bioceramic for making bone tissue engineering scaffolds

Cited by 40 publications

References 58 publications

Vat photopolymerization-based 3D printing of polymer nanocomposites: current trends and applications

Vat photopolymerization-based 3D printing of polymer nanocomposites: current trends and applications

Comprehensive Review on Fabricating Bioactive Ceramic Bone Scaffold Using Vat Photopolymerization

Review of Physical, Mechanical, and Biological Characteristics of 3D-Printed Bioceramic Scaffolds for Bone Tissue Engineering Applications

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