Digital memory device based on tobacco mosaic virus conjugated with nanoparticles

Abstract

Nanostructured viruses are attractive for use as templates for ordering quantum dots to make self-assembled building blocks for next-generation electronic devices. So far, only a few types of electronic devices have been fabricated from biomolecules due to the lack of charge transport through biomolecular junctions. Here, we show a novel electronic memory effect by incorporating platinum nanoparticles into tobacco mosaic virus. The memory effect is based on conductance switching, which leads to the occurrence of bistable states with an on/off ratio larger than three orders of magnitude. The mechanism of this process is attributed to charge trapping in the nanoparticles for data storage and a tunnelling process in the high conductance state. Such hybrid bio-inorganic nanostructures show promise for applications in future nanoelectronics.

Fluorogenic click reaction

“…This virus has been applied in different areas such as nanoelectronics and energy harvesting devices. [37][38][39][40][41] Wang and coworkers introduced triple bonds on the tyrosine residues of TMV by electrophilic substitution reaction at the ortho position of the phenol ring. Then the alkyne-modified TMV 23 were reacted with non-fluorescent azido derivatives via the CuAAC reaction to afford fluorescently labeled particles 24 (Scheme 7).…”

Mechanistic study of the hydrothermal reduction of palladium on the Tobacco mosaic virus

“…Materials created from TMV virions have been applied to electroless deposition 60 , battery electrodes 60 , memory devices 70 , chemical sensing 29 71 , catalysis 72 , solgel chemistry 46 .…”

“…Platinum nanocluster deposition on TMV showed memory storage properties believed to be caused by the CPs coulomb blockage between the RNA aromatic groups and platinum particles 70 . TMV virions which were assembled on gold substrates and then coated with nickel have been applied as a battery electrode [Liz paper].…”

Phototunable Biomemory Based on Light‐Mediated Charge Trap

“…In addition, biomaterials allow a biocompatible interface between electronic devices and biological worlds, thus broadening corresponding biotechnological and medicinal applications, such as implantable chips, artificial neurons, and electronic skin 20, 21, 22, 23, 24. Various types of biomaterials have been used as active units for fabrication of data‐storage devices, such as protein, polysaccharide, nucleic acid, and virus 25, 26, 27, 28, 29, 30. Due to versatile properties, such as biodegradability, biocompatibility, bioresorbability, optical transparency, and light weight, proteins, the most readily accessible biomolecules can be used as an attractive building blocks for the development of RRAM devices and endow these electronic memories with excellent performance and environmental benignity 31, 32.…”