Digital microfluidics: A promising technique for biochemical applications

He, Wenping; Chen, Liguo; Sun, Lining

doi:10.1007/s11465-017-0460-z

Cited by 66 publications

(49 citation statements)

References 75 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Microfluidics device installed on a fluorescence microscope has yielded valuable information regarding the kinetics of viral infection in single cells and variability of cellular factors regulating the viral replication (Guo et al, 2017). Hybrid microfluidics using either active or passive approaches or their combination, integration of nano-and microfluidics, digital or virtual microfluidics are the emerging microfluidic platforms which are being recently introduced for high throughput and continuous single cell isolation avoiding the general limitations of the existing technique (Xu et al, 2016;Yan et al, 2016;Wang et al, 2017;Vanderpoorten et al, 2019). Direct sampling through nano-electrospray ionization tips followed by mass spectrometric analyses method is gaining popularity in recent times due to its minimum sample requirement and processing along with high throughput data generation.…”

Section: Sample Preparation Methods For Single Cell Isolation For Scmmentioning

confidence: 99%

Single Cell Metabolomics: A Future Tool to Unmask Cellular Heterogeneity and Virus-Host Interaction in Context of Emerging Viral Diseases

et al. 2020

View full text Add to dashboard Cite

Section: Sample Preparation Methods For Single Cell Isolation For Scmmentioning

confidence: 99%

Single Cell Metabolomics: A Future Tool to Unmask Cellular Heterogeneity and Virus-Host Interaction in Context of Emerging Viral Diseases

et al. 2020

View full text Add to dashboard Cite

“…P-DMF devices, which have performances similar to those of other DMF devices, are novel microfluidic platforms because they can be used to manipulate small-volume droplets independently without the need for channels, pumps, and microvalves; thus, this type of microfluidic device, the p-DMF device, is most suitable for multi-step assay protocols, as well as for other single-step assay protocols [33,107]. In addition to their abilities to transport fluid and delay its flow, p-DMF devices can mix two or more samples effectively to allow homogeneous mixing between a sample and a reagent.…”

Section: Biomarker Detection By Using Programmable P-dmf Devicesmentioning

confidence: 99%

Programmable Paper-Based Microfluidic Devices for Biomarker Detections

et al. 2019

View full text Add to dashboard Cite

Recent advanced paper-based microfluidic devices provide an alternative technology for the detection of biomarkers by using affordable and portable devices for point-of-care testing (POCT). Programmable paper-based microfluidic devices enable a wide range of biomarker detection with high sensitivity and automation for single- and multi-step assays because they provide better control for manipulating fluid samples. In this review, we examine the advances in programmable microfluidics, i.e., paper-based continuous-flow microfluidic (p-CMF) devices and paper-based digital microfluidic (p-DMF) devices, for biomarker detection. First, we discuss the methods used to fabricate these two types of paper-based microfluidic devices and the strategies for programming fluid delivery and for droplet manipulation. Next, we discuss the use of these programmable paper-based devices for the single- and multi-step detection of biomarkers. Finally, we present the current limitations of paper-based microfluidics for biomarker detection and the outlook for their development.

show abstract

Section: Biomarker Detection By Using Programmable P-dmf Devicesmentioning

confidence: 99%

Micro- and Nanofluidics for Bionanoparticle Analysis

Zeng¹,

Cheng²

2019

View full text Add to dashboard Cite

of Surgery at Massachusetts General Hospital. The focus of her research is to develop microfluidic devices for cell and pathogen analysis. In combination with nanomaterials and biosensors, these microfluidic devices are expected to perform automated sample processing and sensitive analyte detection towards point-of-care uses. She has published more than 60 referred technical papers, has been granted several U.S. patents and has obtained research funding from NIH, NSF, and DoD.Yong Zeng currently is a Docking Scholar Associate Professor in the

show abstract

Digital microfluidics: A promising technique for biochemical applications

Cited by 66 publications

References 75 publications

Single Cell Metabolomics: A Future Tool to Unmask Cellular Heterogeneity and Virus-Host Interaction in Context of Emerging Viral Diseases

Single Cell Metabolomics: A Future Tool to Unmask Cellular Heterogeneity and Virus-Host Interaction in Context of Emerging Viral Diseases

Programmable Paper-Based Microfluidic Devices for Biomarker Detections

Micro- and Nanofluidics for Bionanoparticle Analysis

Contact Info

Product

Resources

About