The Special Issue of the Manufacturing Engineering Society 2019 (SIMES-2019) has been launched as a joint issue of the journals “Materials” and “Applied Sciences”. The 29 contributions published in this Special Issue of Materials present cutting-edge advances in the field of manufacturing engineering focusing on additive manufacturing and 3D printing, advances and innovations in manufacturing processes, sustainable and green manufacturing, manufacturing of new materials, metrology and quality in manufacturing, industry 4.0, design, modeling, and simulation in manufacturing engineering and manufacturing engineering and society. Among them, these contributions highlight that the topic “additive manufacturing and 3D printing” has collected a large number of contributions in this journal because its huge potential has attracted the attention of numerous researchers over the last years.