Dimensions of quality of life in the different stages of chronic kidney disease patients – A cross-sectional study

Abstract

Background: Chronic Kidney Disease (CKD) is an emerging disease that causes morbidity, mortality and affects patient's quality of life (QoL). Objectives: To assess and compare dimensions of QoL in the different stages of CKD patients and also to identify the factors affecting QoL. Data and methods: A cross-sectional study was carried out for a period of 8 months in the Dept. of Nephrology. The inclusion criterion of the study is patients above 18 years age diagnosed with CKD stage 3-5 and patients undergoing maintenance haemodialysis. The patients were assessed for QoL using European-QoL-5-dimensional (EQ-QoL-5D) and visual analog scale (VAS) questionnaires. Results: Out of 210 patients, most of the patients were in the age group 51-65 years (43.33%) and the mean age of study population was 52 ± 16.04. In the present study, most of the patients were males (79.04%). The most common comorbidities were hypertension (90%) and 51% of diabetes mellitus (DM). The mean EQ-5D index scores of the CKD stage 3, 4, 5 and 5D patients were 0.77 ± 0.09, 0.67 ± 0.10, 0.62 ± 0.12 and 0.50 ± 0.15 and the mean VAS scores for these stages were 74.10 ± 7.68, 66.52 ± 10.90, 66.45 ± 8.80 and 55.04 ± 12.82 respectively. Conclusion: The most commonly affected domains were usual activities (79%), pain (76.20%) and anxiety/depression (71.91%). Factors such as age (> 65 yrs), BMI (Underweight and Obese), educational background (Illiterate), Unemployment, domiciliary status (Rural), number of medications (> 11) had significant association with EQ-5D index and VAS scores (p-0.000). It was found that QoL was impaired in stage 5D compared to other stages (p-0.000).

Health Related Quality of Life: Chronic Kidney Disease Dengan Hemodialisa Menggunakan Instrumen Eq-5d-5l Di Pekanbaru

“…Berdasarkan kategori jenis kelamin, laki-laki (56,6%) lebih banyak yang mengalami CKD dengan HD dibandingkan perempuan (43,4%). Penelitian sejenis menunjukkan laki-laki lebih banyak dibanding perempuan di India dengan persentase 79,04% (20) , di Palestina sebanyak 52,1%, dan sebanyak 1027 pasien (60,5%) di Australia, New Zealand, Canada, dan Spanyol (2) . Stage pada penelitian ini disesuaikan berdasarkan stage CKD yaitu stage 4 dan 5 dengan persentase 7,4% dan 92,6%.…”