Direct-Current Electrical Stimulation of Tendon Healing in Vitro

Nessler, Joseph P.; Mass, Daniel P.

doi:10.1097/00003086-198704000-00032

Cited by 68 publications

(42 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…It resulted in increased ultimate strength of the tendon in both in vitro and in vivo studies. Nessler 82 looked at regenerating rabbit flexor tendons cultured in a cell-free medium. A stainless-steel electrode was used to provide a high electric-current medium.…”

Section: Grossmentioning

confidence: 99%

Acute and Chronic Tendon Injuries: Factors Affecting the Healing Response and Treatment

Sandrey¹

2003

Journal of Sport Rehabilitation

View full text Add to dashboard Cite

Objective: Tendons have biomechanical properties based on collaborative remodeling of all their cells through normal lysis and synthesis. This review assesses factors that affect the healing response and presents solutions for rehabilitating acute and chronic tendon injuries. Data Sources: MEDLINE (1970MEDLINE ( -2002 and SPORTDiscus (1970SPORTDiscus ( -2002. Key words searched were tendon, tendinitis, tendinosis, tendinopathy, rehabilitation, ultrasound, NSAIDs, exercise, mobilization, aging, immobilization, and healing. Data Synthesis: The biomechanical roles tendons play change throughout one's lifetime and are influenced by maturation and aging, injury and healing, immobilization, exercise, medications, and therapeutic modalities. Suggestions from animal, case, and clinical studies are varied but provide solutions in the treatment of acute and chronic tendon injuries. Conclusions and Recommendations: All factors that affect the tendon structure should be considered in a rehabilitation program. Therapeutic exercise, medications, or therapeutic modalities should never be used as a stand-alone therapy. Key Words: inflammation, tendinitis, tendinosis, aging, rehabilitation Sandrey MA. Acute and chronic tendon injuries: factors affecting the healing response and treatment. J Sport Rehabil. 2003;12:70-91.

show abstract

Section: Grossmentioning

confidence: 99%

Acute and Chronic Tendon Injuries: Factors Affecting the Healing Response and Treatment

Sandrey¹

2003

Journal of Sport Rehabilitation

View full text Add to dashboard Cite

show abstract

“…Results suggest that MENS offers pain relief 21) and promotes soft tissue repair. Furthermore, it has been also reported that MENS facilitates the regeneration of tendon injuries 22) 23) , skin ulcers 24) 25) , wounds 26)27) , bedsores 28) , ligament injuries 29) , and skeletal muscle injuries 20) . Considering the effects of both therapies, a combined therapy of MENS with icing may be useful for the regeneration of injured skeletal muscle.…”

Section: Introductionmentioning

confidence: 97%

Regeneration of Injured Tibialis Anterior Muscle in Mice in Response to Microcurrent Electrical Neuromuscular Stimulation with or without Icing

Yoshida

Fujiya

Goto

et al. 2015

J St. Marianna Univ

View full text Add to dashboard Cite

Objective: Cold therapy, so-called icing, is often used immediately after muscle injuries as first aid for the suppression of inflammation and pain relief. Recent evidences show icing retards the regeneration of injured skeletal muscle. On the other hand, microcurrent electrical neuromuscular stimulation (MENS) promotes the regeneration of injured skeletal muscle. In this study, we investigated the effects of the MENS with or without icing on the regeneration of injured skeletal muscle. Methods: Eight-week-old male mice (C57BL/6J) were divided into 4 groups: control (C), cardiotoxin (CTX) injected (X), CTX injected with MENS (XM), and CTX injected with combined treatments with icing and MENS (XIM) groups. Necrosis-regeneration cycle was induced by an intramuscular injection of CTX into tibialis anterior (TA) muscles except for C group. After CTX-injection, the hindlimbs of the mice were soaked in ice-cold water (4ºC) for 20 minutes under anesthesia (XIM). After the treatments, both right and left hindlimbs of the mice in XIM and XM groups were treated with MENS (10 µA, 0.3 Hz, 250 msec) for 60 min a day and 3 days per week for 1 or 3 weeks. One and three weeks after CTX injection, TA muscles were dissected. Results: MENS with or without icing facilitated the recovery of muscle protein content and muscle fiber morphology including mean fiber cross-sectional areas of injured TA muscle, compared with non-treated condition. These facilitating effects of MENS with or without icing were accompanied with the increase in the relative number of Pax7-positive nuclei, namely satellite cells. Judging from fiber morphology, MENS with icing had enhanced stimulating effects on the regeneration of injured skeletal muscle, compared with MENS-treated condition. Conclusion: Evidence suggested that MENS with or without icing facilitated the regeneration of injured TA muscle. A combination treatment of MENS with icing might be a useful therapy for sports-related skeletal muscle injuries.

show abstract

“…In orthopedics, electrical stimulation by direct and alternating electric currents using invasive or semi-invasive methods, pulsing electromagnetic fields and capacitively coupled electric fields, magnetic stimulation, and ultrasound stimulation were applied to patients, and elevation of the bone mineral density and good bone restoration were observed [2][3][4][5][6][7][8][9][10][11][12] . Recently, good results were obtained in both in vivo [13][14][15][16][17] studies and in vitro studies using cultured bone and surrounding tissue-derived tissues and cells [18][19][20][21][22][23][24][25][26] . However, very few studies of this area were available in the dental field 27,28) .…”

Section: Introductionmentioning

confidence: 99%

Intraoral conversion of occlusal force to electricity and magnetism by biting of piezoelectric elements

et al. 2012

View full text Add to dashboard Cite

Very weak electrical, magnetic and ultrasound signal stimulations are known to promote the formation, metabolism, restoration and stability of bone and surrounding tissues after treatment and operations. We have therefore investigated the possibility of intraoral generation of electricity and magnetism by occlusal force in an in vitro study. Biting bimorph piezoelectric elements with lead zirconate titanate (PZT) using dental models generated appropriate magnetism for bone formation, i.e. 0.5-0.6 gauss, and lower electric currents and higher voltages, i.e. 2.0-6.0 μA at 10-22 V (appropriate levels are 30 μA and 1.25 V), as observed by a universal testing machine. The electric currents and voltages could be changed using amplifier circuits. These results show that intraoral generation of electricity and magnetism is possible and could provide post-operative stabilization and activation of treated areas of bone and the surrounding tissues directly and/or indirectly by electrical, magnetic and ultrasound stimulation, which could accelerate healing.

show abstract

Direct-Current Electrical Stimulation of Tendon Healing in Vitro

Cited by 68 publications

References 0 publications

Acute and Chronic Tendon Injuries: Factors Affecting the Healing Response and Treatment

Acute and Chronic Tendon Injuries: Factors Affecting the Healing Response and Treatment

Regeneration of Injured Tibialis Anterior Muscle in Mice in Response to Microcurrent Electrical Neuromuscular Stimulation with or without Icing

Intraoral conversion of occlusal force to electricity and magnetism by biting of piezoelectric elements

Contact Info

Product

Resources

About