Direct evidence for extensive paternal mitochondrial DNA inheritance in the marine mussel Mytilus

Ζούρος, Ε.; Freeman, K. R.; Ball, Amy Oberhauser; Pogson, Grant H.

doi:10.1038/359412a0

Cited by 194 publications

(129 citation statements)

References 19 publications

Supporting

Mentioning

113

Contrasting

Unclassified

Order By: Relevance

“…At present, the occurrence of paternal leakage remains heteroplasmic, containing different mitochondrial allelic types. During past years, many studies have shown controversial, except for some peculiar inheritance systems as in mussels, where paternal transmission has that heteroplasmy may be more common than previously thought, due to the constant input of new mutabeen clearly demonstrated (Zouros et al 1992;Skibinski et al 1994). In Drosophila, paternal transmission tions (Corral-Debrinski et al 1992;Cortopassi et al 1992;Jazin et al 1996;Lightowlers et al 1997;Michi-has been detected in both interspecific and intraspecific crosses (Kondo et al 1990(Kondo et al , 1992.…”

mentioning

confidence: 99%

Germline Bottlenecks, Biparental Inheritance and Selection on Mitochondrial Variants

2005

View full text Add to dashboard Cite

Selection on mitochondrial mutations potentially occurs at different levels: at the mitochondria, cell, and organism levels. Several factors affect the strength of selection at these different levels; in particular, mitochondrial bottlenecks during germline development and reduced paternal transmission decrease the genetic variance within cells, while they increase the variance between cells and between organisms, thus decreasing the strength of selection within cells and increasing the strength of selection between cells and organisms. However, bottlenecks and paternal transmission also affect the effective mitochondrial population size, thus affecting genetic drift. In this article, we use a simple model of a unicellular life cycle to investigate the effects of bottlenecks and paternal transmission on the probability of fixation of mitochondrial mutants and their frequency at mutation-selection equilibrium. We find that bottlenecks and reduced paternal transmission decrease the mean frequency of alleles with s m Ͼ s c (approximately), where s m and s c are the strengths of selection for an allele within and between cells, respectively, and increase the frequency of alleles with s m Ͻ s c . Effects on fixation probabilities are different; for example, bottlenecks reduce the fixation probability of mutants with s m Ͼ 0 (unless s m is very small relative to s c ) and increase the fixation probability of mutants with s m Ͻ 0.

show abstract

mentioning

confidence: 99%

Germline Bottlenecks, Biparental Inheritance and Selection on Mitochondrial Variants

2005

View full text Add to dashboard Cite

show abstract

“…Crosses between Mytilus edulis with rather divergent mtDNA showed total exclusion of paternal mtDNA within oocytes, whereas incomplete exclusion of maternal mtDNA took place within sperm (Zouros et at., 1992;Skibinski et a!., 1994). Following a paternal contribution, a given individual has heteroplasmic somatic cells whenever its parents did not carry the same mtDNA type and the nature of its progeny (homoplasmic or heteroplasmic) will mostly depend on the type of mtDNA of its mate.…”

mentioning

confidence: 99%

Nonrandom partition of mitochondria in heteroplasmic Drosophila

Stordeur

1997

Heredity

View full text Add to dashboard Cite

In order to understand the status of heteroplasmy and its evolution within the Drosophila melanogaster subgroup, cytoplasm microinjections between eggs were performed involving three lineages of Drosophila simulans, carrying the siT, sill or silil mtDNA type, respectively, and two strains of Drosophila mauritiana carrying the maT or mall mtDNA type. Progeny of eggs from all combinations of injection were analysed. The mall or sil molecules, when provided by the donor, were never detected in the offspring of the hosts, whatever the host's mitochondrial type. Heteroplasmic flies were detected when sill, suIT or mal mitochondria were injected into any of the other cytoplasms. In the majority of cases the percentage of foreign mtDNA increased over generations, leading to a complete replacement of the endogenous mtDNA. In most cases, sill was prevalent. The stochastic processes involved in the evolution of heteroplasmic states are strongly affected by selective values of the different mtDNA types, with a clear hierarchy among them: sill has the most advantage, then sill! and maT, and finally siT and mall. In the sill/mall heteroplasmy case, the loss of mall was more rapid at a high temperature.

show abstract

“…The Unionidae and two other bivalve families (Mytilidae and Veneridae) possess two different mitochondrial genomes (mitotypes) that are associated with gender (F for female and M for male) (Zouros et al, 1992(Zouros et al, , 1994Hoeh et al, 1996Hoeh et al, , 1997Liu et al, 1996;Passamonti & Scali, 2001). These sexual mitotype lineages remain separate via doubly uniparental inheritance (DUI) (Skibinski et al, 1994;Zouros et al, 1994), where the maternal mitochondrial genome (F-mitotype) is inherited by both male and female progeny from the mother, while the paternal mitochondrial genome (M-mitotype) is only transmitted from father to male offspring and housed in the male gonads.…”

mentioning

confidence: 99%

Congruence and Conflict Between Molecular and Reproductive Characters When Assessing Biological Diversity in the Western Fanshell Cyprogenia aberti (Bivalvia, Unionidae)¹

Serb

Barnhart

2008

Annals of the Missouri Botanical Garden

View full text Add to dashboard Cite

Organisms with complex life histories and unusual modes of genome inheritance can present challenges for phylogenetic reconstruction and accurate assessment of biological diversity. This is particularly true for freshwater bivalves in the family Unionidae because: (1) they have complex life cycles that include a parasitic larva and obligate fish host; (2) they possess both a male and female mitochondrial genome that is transmitted through doubly uniparental inheritance (DUI); and (3) they are found in riverine habitats with complex hydrogeological histories. Examination of mitochondrial DNA (mtDNA) sequences, conglutinate morphology, and host fish compatibility of the western fanshell Cyprogenia aberti (Conrad, 1850) revealed significant character variation across its range. Although variation was correlated among the different data sets and supports discrete groups, these groups did not always correspond to geographically isolated populations. Two discrete mtDNA clades exist sympatrically within most C. aberti populations, and these same clades are also diagnosed by at least one morphological character, egg color. The surprisingly high genetic distance (14. 61%-20.19%) between the members of these sympatric clades suggests heritance infidelity of the two different mitochondrial genomes. This hypothesis was tested and falsified. More general patterns in geography were observed in host fish compatibility. Populations of C. aberti from the major river systems differed in their ability to utilize fish species as hosts. These differences in reproductive traits, which are presumably genetically based, suggest that these populations are not ecologically exchangeable with one another and represent biological diversity not previously recognized within Cyprogenia Agassiz, 1852. KeywordsCentral Highlands, coevolution, Cyprogenia aberti, double uniparental inheritance, mitotype, Unionidae Disciplines Ecology and Evolutionary Biology | Genetics and Genomics CommentsThis article is from Annals of the Missouri Botanical Garden 95 (2008) ABSTRACTOrganisms with complex life histories and unusual modes of genome inheritance can present challenges for phylogenetic reconstruction and accurate assessment of biological diversity. This is particularly true for freshwater bivalves in the family Unionidae because: (1) they have complex life cycles that include a parasitic larva and obligate fish host; (2) they possess both a male and female mitochondrial genome that is transmitted through doubly uniparental inheritance (DUI); and (3) they are found in riverine habitats with complex hydrogeological histories. Examination of mitochondrial DNA (mtDNA) sequences, conglutinate morphology, and host fish compatibility of the western fanshell Cyprogenia aberti (Conrad, 1850) revealed significant character variation across its range. Although variation was correlated among the different data sets and supports discrete groups, these groups did not always correspond to geographically isolated populations. Two discrete mtDNA clades exist ...

show abstract

Direct evidence for extensive paternal mitochondrial DNA inheritance in the marine mussel Mytilus

Cited by 194 publications

References 19 publications

Germline Bottlenecks, Biparental Inheritance and Selection on Mitochondrial Variants

Germline Bottlenecks, Biparental Inheritance and Selection on Mitochondrial Variants

Nonrandom partition of mitochondria in heteroplasmic Drosophila

Congruence and Conflict Between Molecular and Reproductive Characters When Assessing Biological Diversity in the Western Fanshell Cyprogenia aberti (Bivalvia, Unionidae)¹

Contact Info

Product

Resources

About

Direct evidence for extensive paternal mitochondrial DNA inheritance in the marine mussel Mytilus

Cited by 194 publications

References 19 publications

Germline Bottlenecks, Biparental Inheritance and Selection on Mitochondrial Variants

Germline Bottlenecks, Biparental Inheritance and Selection on Mitochondrial Variants

Nonrandom partition of mitochondria in heteroplasmic Drosophila

Congruence and Conflict Between Molecular and Reproductive Characters When Assessing Biological Diversity in the Western Fanshell Cyprogenia aberti (Bivalvia, Unionidae)1

Contact Info

Product

Resources

About

Congruence and Conflict Between Molecular and Reproductive Characters When Assessing Biological Diversity in the Western Fanshell Cyprogenia aberti (Bivalvia, Unionidae)¹