Germline Bottlenecks, Biparental Inheritance and Selection on Mitochondrial Variants

Roze, Denis; Rousset, François; Michalakis, Yannis

doi:10.1534/genetics.104.039495

Cited by 44 publications

(75 citation statements)

References 76 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Plainly, this is sufficient to maintain mitonuclear function, as predicted by our model. Our model also has implications for multi-cellular organisms, where true germline bottlenecking occurs [21,22]. In line with our results, true bottlenecks are only observed in large organisms with large numbers of mitochondria [25 -27].…”

Section: Discussionsupporting

confidence: 83%

Selection for mitonuclear co-adaptation could favour the evolution of two sexes

et al. 2011

View full text Add to dashboard Cite

Mitochondria are descended from free-living bacteria that were engulfed by another cell between one and a half to two billion years ago. A redistribution of DNA led to most genetic information being lost or transferred to a large central genome in the nucleus, leaving a residual genome in each mitochondrion. Oxidative phosphorylation, the most critical function of mitochondria, depends on the functional compatibility of proteins encoded by both the nucleus and mitochondria. We investigate whether selection for adaptation between the nuclear and mitochondrial genomes (mitonuclear co-adaptation) could, in principle, have promoted uniparental inheritance of mitochondria and thereby the evolution of two mating types or sexes. Using a mathematical model, we explore the importance of the radical differences in ploidy levels, sexual and asexual modes of inheritance, and mutation rates of the nucleus and mitochondria. We show that the major features of mitochondrial inheritance, notably uniparental inheritance and bottlenecking, enhance the co-adaptation of mitochondrial and nuclear genes and therefore improve fitness. We conclude that, under a wide range of conditions, selection for mitonuclear co-adaptation favours the evolution of two distinct mating types or sexes in sexual species.

show abstract

Section: Discussionsupporting

confidence: 83%

Selection for mitonuclear co-adaptation could favour the evolution of two sexes

et al. 2011

View full text Add to dashboard Cite

show abstract

“…Mutations occurring during the development of the colony could still create some diversity in the large zooxanthella population, but in that case less diversity would be expected within than among colonies. Otherwise, some form of horizontal transfer of symbionts (or, for cytoplasmic organelles, biparental inheritance) has to be invoked to explain the diversity pattern we observe (Roze et al 2005). Since we show a significant within-colony diversity, horizontal transfer of symbionts among colonies might be frequent.…”

Section: Symbiont Genetic Diversitymentioning

confidence: 93%

Symbiont diversity is not involved in depth acclimation in the Mediterranean sea whip Eunicella singularis

Forcioli¹,

Merle²,

Caligara³

et al. 2011

Mar. Ecol. Prog. Ser.

View full text Add to dashboard Cite

In symbiotic cnidarians, acclimation to depth and lower irradiance can involve physio logical changes in the photosynthetic dinoflagellate endosymbiont, such as increased chlorophyll content, or qualitative modifications in the symbiont population in favour of better adapted strains. It has been argued that a lack of capacity to acquire new symbionts could limit the bathymetric distribution of the host species, or compromise its long-term survival in a changing environment. But is that always true? To address this question, we investigated the symbiont genetic diversity in Eunicella singularis, a Mediterranean sea whip species with a wide bathymetric distribution (10 to 50 m depth), which has recently suffered from mass mortalities after periods of abnormally high sea temperatures. We measured symbiont population densities and chlorophyll content in natural populations, and followed the response of the holobionts after reciprocal transplantations to deep and shallow depths. A total of 161 colonies were sampled at 2 depths (10 and 30 m) at 5 sites in the northwestern Mediterranean. All colonies harboured a single ribosomal Symbiodinium clade (A'), but a relatively high within-clade genetic diversity was found among and within colonies. This diversity was not structured by depth, even though the deeper colonies contained significantly lower population densities of symbionts and less chlorophyll. We did, however, reveal host-symbiont specificity among E. singularis and other Mediterranean cnidarian species. Transplantation experiments revealed a limit of plasticity for symbiont population density and chlorophyll content, which in turn questions the importance of the trophic role of Symbiodinium in E. singularis.

show abstract

“…Further, in a recent comment on the various possible mechanisms leading to the evolution of cooperation, Nowak (2) states that the group selection model of T&N results in a different process than kin selection. These are surprising statements, given that many authors have emphasized that group selection models are not different from kin selection models (3-8), and that kin selection theory has been extended to finite populations that can follow very diverse demographic regimes (8)(9)(10)(11)(12)(13)(14). To us, the mechanism favoring cooperation in T&N's model is clearly kin selection.…”

mentioning

confidence: 99%

Group selection and kin selection: Two concepts but one process

Lehmann

Keller

West

et al. 2007

Proc. Natl. Acad. Sci. U.S.A.

Self Cite

253

167

View full text Add to dashboard Cite

In a recent paper, Traulsen and Nowak use a multilevel selection model to show that cooperation can be favored by group selection in finite populations [Traulsen A, Nowak M (2006) Proc Natl Acad Sci USA 103:10952-10955]. The authors challenge the view that kin selection may be an appropriate interpretation of their results and state that group selection is a distinctive process ''that permeates evolutionary processes from the emergence of the first cells to eusociality and the economics of nations.'' In this paper, we start by addressing Traulsen and Nowak's challenge and demonstrate that all their results can be obtained by an application of kin selection theory. We then extend Traulsen and Nowak's model to life history conditions that have been previously studied. This allows us to highlight the differences and similarities between Traulsen and Nowak's model and typical kin selection models and also to broaden the scope of their results. Our retrospective analyses of Traulsen and Nowak's model illustrate that it is possible to convert group selection models to kin selection models without disturbing the mathematics describing the net effect of selection on cooperation.T raulsen and Nowak (1) (T&N) present a multilevel selection model and demonstrate that a mutant helping allele can be favored to fixation, when introduced as a single copy in a population monomorphic for selfishness ifwhere c is the cost of helping, b the benefit of helping for group members (excluding the actor), N the group size, n g the number of groups, the migration rate between groups, and q the probability of group splitting (T&N, inequality ineq. 2). In their conclusion, T&N challenge the view that kin selection is an appropriate interpretation of their results and state that:''It would be interesting to see how the mathematical methods of kin selection can be used to derive our central results given by eqs. 1-3 and what assumption are needed for such a derivation. The problem is that typical methods of kin selection are based on traditional considerations of evolutionary stability, which are not decisive for games in finite populations.'' Further, in a recent comment on the various possible mechanisms leading to the evolution of cooperation, Nowak (2) states that the group selection model of T&N results in a different process than kin selection. These are surprising statements, given that many authors have emphasized that group selection models are not different from kin selection models (3-8), and that kin selection theory has been extended to finite populations that can follow very diverse demographic regimes (8)(9)(10)(11)(12)(13)(14). To us, the mechanism favoring cooperation in T&N's model is clearly kin selection. Indeed, kin selection operates whenever interactions occur among genetic relatives, that is, among individuals who tend to share a more recent common ancestor than individuals sampled randomly from the whole population. This may happen when interactions take place within families before the dispersal of offspring, or whe...

show abstract

Germline Bottlenecks, Biparental Inheritance and Selection on Mitochondrial Variants

Cited by 44 publications

References 76 publications

Selection for mitonuclear co-adaptation could favour the evolution of two sexes

Selection for mitonuclear co-adaptation could favour the evolution of two sexes

Symbiont diversity is not involved in depth acclimation in the Mediterranean sea whip Eunicella singularis

Group selection and kin selection: Two concepts but one process

Contact Info

Product

Resources

About