Direct reuse of electronic plastic scraps from computer monitor and keyboard to direct stem cell growth and differentiation

Shi, Pujiang; Tan, Chiew Kei; Wu, Zhuoran; Gabriel, Jean‐Christophe P.; Srinivasan, Madhavi; Lee, Jongmin; Tay, Chor Yong

doi:10.1016/j.scitotenv.2021.151085

Cited by 10 publications

(2 citation statements)

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“…WEEE plastics were also investigated as cell culture substrates and showed promising results for cell growth and differentiation due to their surface properties. 259…”

Section: Resultsmentioning

confidence: 99%

“…WEEE plastics were also investigated as cell culture substrates and showed promising results for cell growth and differentiation due to their surface properties. 259 Overall, recycling of waste polymers from WEEE was more studied than polymers from end-of-life materials from renewable energy and energy storage technologies. Recycled EVA was investigated as a raw material to produce bituminous binders.…”

Section: State Of the Art Of The Recycling Techniquesmentioning

confidence: 99%

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A toolbox for improved recycling of critical metals and materials in low-carbon technologies

Zante,

Elgar,

Hartley

et al. 2024

RSC Sustain.

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“…WEEE plastics were also investigated as cell culture substrates and showed promising results for cell growth and differentiation due to their surface properties. 259…”

Section: Resultsmentioning

confidence: 99%

Section: State Of the Art Of The Recycling Techniquesmentioning

confidence: 99%

A toolbox for improved recycling of critical metals and materials in low-carbon technologies

Zante,

Elgar,

Hartley

et al. 2024

RSC Sustain.

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show abstract

Label‐Free Single Microparticles and Cell Aggregates Sorting in Continuous Cell‐Based Manufacturing

Gong,

He,

et al. 2024

Adv Healthcare Materials

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There is a paradigm shift in biomanufacturing towards continuous bioprocessing but cell‐based manufacturing using adherent and suspension cultures including microcarriers, hydrogel microparticles and 3D cell aggregates remains challenging due to the lack of efficient in‐line bioprocess monitoring and cell harvesting tools. Herein, we report a novel label‐free microfluidic platform for high throughput (∼ 50 particles/sec) impedance bioanalysis of biomass, cell viability and stem cell differentiation at single particle resolution. The device is integrated with a real‐time piezo‐actuated particle sorter based on user‐defined multi‐frequency impedance signatures. We first performed biomass profiling of Cytodex‐3 microcarriers seeded with adipose‐derived mesenchymal stem cells (ADSCs) to sort well‐seeded or confluent microcarriers for downstream culture or harvesting, respectively. Next, we demonstrated impedance‐based isolation of microcarriers with osteogenic differentiated ADSCs which was validated with a two‐fold increase of calcium content in sorted ADSCs. Impedance profiling of heterogenous ADSCs‐encapsulated hydrogel (alginate) microparticles and 3D ADSC aggregate mixtures was also performed to sort particles with high biomass and cell viability to improve cell quality. Overall, the scalable microfluidic platform technology enables in‐line sample processing from bioreactors directly and automated analysis of cell quality attributes to maximize cell yield and improve the control of cell quality in continuous cell‐based manufacturing.This article is protected by copyright. All rights reserved

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Poly(lactic acid)/poly (butylene succinate)/boron nitride nanosheet composites with high thermal conductivity: a novel biodegradable electronic packaging material

Tian¹,

Bai²,

Chen³

et al. 2023

Polym. Bull.

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Direct reuse of electronic plastic scraps from computer monitor and keyboard to direct stem cell growth and differentiation

Cited by 10 publications

References 50 publications

A toolbox for improved recycling of critical metals and materials in low-carbon technologies

A toolbox for improved recycling of critical metals and materials in low-carbon technologies

Label‐Free Single Microparticles and Cell Aggregates Sorting in Continuous Cell‐Based Manufacturing

Poly(lactic acid)/poly (butylene succinate)/boron nitride nanosheet composites with high thermal conductivity: a novel biodegradable electronic packaging material

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