Direct Synthesis of Metal-Complexed Aromatic Amino Acid Derivatives by Palladium-Catalysed Coupling Processes

First Synthesis of Ferrocenyl-N-Alkylaminophosphonic Acids

“…12 Therefore, various molecular switches containing a ferrocene moiety have been synthesized. [12][13][14] The syntheses of ferrocenylalanine 15,16 and 1,1-ferrocenyl-bis-(alanine) 17 were also reported.…”

Synthesis of ferrocenoyl amino acid derivatives via homogeneous catalytic aminocarbonylation

“…Although iodoferrocene has been used as substrate for the synthesis of protected ferrocenyl-alanine ((2-amino-2-carboxyethyl)ferrocene) derivatives via homogeneous catalytic coupling reactions [19,20], to the best of our knowledge there is no precedence for the synthesis of N-ferrocenoyl amino acids with palladium-catalysed aminocarbonylation.…”

Aminocarbonylation of 1,1′-diiodoferrocene, two-step synthesis of heterodisubstituted ferrocene derivatives via homogeneous catalytic carbonylation/coupling reactions

“…As palladium-catalysed coupling reactions of 1,1 0 -diiodoferrocene with organotin [11] and organozinc compounds [12] have been reported to lead to mixtures of 1-substituted-1 0 -iodo-ferrocenes and symmetrical 1,1 0 -disubstituted derivatives, we decided to explore the palladium-catalysed aminocarbonylation of the same substrate in detail.…”