Direct Visual Inspection of the Cervix With Lugol Iodine for the Detection of Premalignant Lesions

El-Shalakany, Amr; Saeed, Mohammed M.; Abdel-Aal, Mohammed Reda; Elnakeeb, Amr Y.; Noseirat, Nael; Ayyad, Sohair B.; Din, Zeinab Sehab El

doi:10.1097/lgt.0b013e31815f527c

Cited by 13 publications

(8 citation statements)

References 24 publications

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“…Moving the test of Lugol's staining (Schiller's test) from the "minor grade" category to the "nonspecific" category of the "abnormal colposcopic findings" section is because several studies such as those associated with the ASCUS-LSIL Triage Study showed poor reliability of Lugol's staining. 14,24,25 A cervical polyp is a common finding and has remained in the "miscellaneous findings," including its origin as being ectocervical or endocervical. …”

Section: Discussionmentioning

confidence: 98%

2011 Colposcopic Terminology of the International Federation for Cervical Pathology and Colposcopy

Bornstein

Bentley

Bösze

et al. 2012

Obstetrics & Gynecology

375

291

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New colposcopy terminology was prepared by the Nomenclature Committee of the International Federation of Cervical Pathology and Colposcopy after a critical review of previous terminologies, online discussions, and discussion with national colposcopy societies and individual colposcopists. This document has been expanded to include terminology of both the cervix and vagina. The popular terms "satisfactory colposcopy" and "unsatisfactory colposcopy" have been replaced. The colposcopic examination should be assessed for three variables: 1) adequate or inadequate, with the reason given; 2) squamocolumnar junction visibility; and 3) transformation zone type. Other additions were the localization of the lesion to either inside or outside the transformation zone and determinants of size as well as location of cervical lesions. Two new signs were included in the terminology-the "inner border sign" and "ridge sign." The following definitions have been added: congenital transformation zone, polyp (ectocervical or endocervical), stenosis, congenital anomaly, and posttreatment consequence. In addition, the terminology includes standardization of cervical excision treatment types and cervical excision specimen dimensions. The International Federation of Cervical Pathology and Colposcopy recommends that the 2011 terminology replace all others and be implemented for diagnosis, treatment, and research.

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Section: Discussionmentioning

confidence: 98%

2011 Colposcopic Terminology of the International Federation for Cervical Pathology and Colposcopy

Bornstein

Bentley

Bösze

et al. 2012

Obstetrics & Gynecology

375

291

View full text Add to dashboard Cite

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“…Most of the studies were from India (n = 11) [28][29][30][31][32][33][34] and Africa (n = 9), 28,[35][36][37][38] with just three studies from Oceania (Vanuatu) 39 and Latin America (Brazil and Columbia). 15,40 Nine different studies, conducted in four Indian and five African cities, were reported in one article.…”

Section: Study Characteristicsmentioning

confidence: 99%

Accuracy of combinations of visual inspection using acetic acid or lugol iodine to detect cervical precancer: a meta‐analysis

Catarino

Schäfer

Vassilakos

et al. 2017

BJOG

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“…15 Previous studies indicated that sensitivity of DVI in identification of pre-cancerous cervix lesions is more than Pap smear. 16 17 18 For example, a study in Tehran showed that, sensitivity of DVI was 96% and its specificity was 44% that were higher than sensitivity and specificity of Pap smear that were 42% and 10% respectively. 9 Another study in 2012, reported the sensitivity and specificity of DVI, 88.8% and 99.9% while they were 37.5% and 99.6% for Pap smear.…”

Section: Discussionmentioning

confidence: 99%

“… 20 Sensitivity of DVI in different studies was reported between 75 to 100% 13 14 15 17 and its specificity was reported between 16 to 85%. 16 17 18 21 Also, it is reported that sensitivity of DVI is higher than Pap smear while its specificity is lower than Pap test. 16 18 22 23 In our study sensitivity and specificity of DVI were 71.4% and 50% compared with 14.3% and 50% respectively for Pap smear.…”

Section: Discussionmentioning

confidence: 99%

Comparing the results of Pap smear and Direct Visual Inspection (DVI) with 5% acetic acid in cervical cancer screening

et al. 2015

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Background:Cervical cancer is the most second common cancer among Iranian women. This study was carried out to compare the results of Pap smear method and Direct Visual Inspection (DVI) with 5% acetic acid in cervical cancer screening in Tabriz, Iran.Material and Methods:This cross-sectional study was carried out in Alzahra Therapeutic-Educational Centre, Tabriz, Iran in 2013 on 1000 women. First, Pap smear was done for all women, and then the cervix exposed with 5% acetic acid by cotton swab for 30 seconds and observed under adequate light. At the end, women with abnormal results in Pap smear or DVI method were referred to colposcopy and biopsy. Test's sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV), LR+, LR- and confidence interval (CI) were determined (P < 0.05).Results:Nine-hundred and seventy-four (94.7%) cases were normal and had no abnormal findings and 26 (2.6%) participants had positive results in Pap smear or DVI test. Twelve women had abnormal Pap smear (nine women with atypical squamous cells of undetermined significance, ASCUS, three women with dysplasia, atypical endocervical, and low-grade squamous intraepithelial lesion, LSIL results) and 14 women had positive DVI (four women with human papillomavirus, HPV or koilocyte,) and one women with abnormality in both method had carcinoma in biopsy that referred to oncologist. In this study the sensitivity, specificity, PPV and NPV for DVI were 71.4%, 50%, 35.7%, and 81.8% respectively in comparison with 14.3%, 50%, 10%, and 60% for Pap smear.Conclusion:As the DVI method has higher sensitivity and positive predictive value than Pap smear, it could be used as a useful method beside the Pap smear.

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Direct Visual Inspection of the Cervix With Lugol Iodine for the Detection of Premalignant Lesions

Cited by 13 publications

References 24 publications

2011 Colposcopic Terminology of the International Federation for Cervical Pathology and Colposcopy

2011 Colposcopic Terminology of the International Federation for Cervical Pathology and Colposcopy

Accuracy of combinations of visual inspection using acetic acid or lugol iodine to detect cervical precancer: a meta‐analysis

Comparing the results of Pap smear and Direct Visual Inspection (DVI) with 5% acetic acid in cervical cancer screening

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