Directed Particle Transport via Reconfigurable Fiber Networks

Abstract

Mass transport limitations of particulates within conventional microanalytical systems are often cited as the root cause for low sensitivity but can be overcome by directed analyte transport, such as via biomolecular motors or gradient surfaces. An ongoing challenge is the development of materials that are passive in nature (i.e., no external power source required), but can reconfigure to perform work, such as transporting particle-based analytes. Mimicking biology's concepts of autonomous and reconfigurable materials systems, like the Drosera capensis leaf, reconfigurable fiber networks that effectively concentrate particulates within a localized spot that can act as a detection patch are developed. These networks, prepared by electrohydrodynamic co-jetting, draw their reconfigurability from a bicompartmental fiber architecture. Upon exposure to neutral pH, a differential swelling of both fiber compartments gives rise to interfacial tension and ultimately results in shape reconfiguration of the fiber network. Compared to free particles, the reconfigurable fiber networks display a 57-fold increase in analyte detectability, average transport efficiencies of 91.9 ± 2.4%, and separation selectivity between different surface properties of 95 ± 3%. The integration of biomimetic materials into microanalytical systems, exemplified in this study, offers ample opportunities to design novel and effective detection schemes that circumvent mass transport limitations.

Fabrication of Zigzag Parylene Nanofibers in Liquid Crystals with Electric Field-Induced Defect Structures

“…Recently, the implementation of fiber structures has been achieved using the chemical vapor polymerization (CVP) method, where the orientation-controlled LC structures with the surface treatment are used as templates. − This development holds significant importance as it demonstrates the potential to produce unique surface structures such as oriented polymeric fiber with diverse functionalities using the various parylene monomers having specific functional moieties through the well-established CVP process. − In the CVP process, the polymerization reaction occurs at the interface through loaded precursors, which penetrate the LC molecules and grow along the long-range order of the LC template. The LC directors as ‘scaffolds’ can be controlled to create a variety of polymer fibrillar structures using external stimuli.…”