In this paper, we consider the scientific, technical, and technological aspects in the field of creating new high-temperature materials for the parts of the hot section of gas turbine engines (GTEs) with operating temperatures exceeding those existing in GTEs. More refractory metallic materials for the creation of new high-melting alloys used in the manufacture of operating and nozzle blades and other parts of promising gas turbine engines based on the Co-Cr, Pt-Al, Nb-Si, and Mo-Si-B systems were studied. In alloys of the Co-Cr system, the high-temperature strength is mainly provided owing to the hardening of the Co matrix, including dispersed precipitates of the carbide phase (TaC) and the boride phase Cr 2 B. In alloys of the Pt-Al system, it is due to alloying with Cr, Al, Ti, Re, etc., and precipitates of the coherently embedded Pt 3 Al phase. In eutectic alloys of the Nb-Si system, it is due to the complex hardening of the Nb solid solution and the Nb 5 Si 3 silicide, as well as the natural compositional structure. In Mo-Si-B alloys, high strength is achieved by alloying with α-Mo solid solution and the formation of intermetallic phases Mo 3 Si and Mo 5 SiB 2 and carbides Mo 2 C and TiC. We selected compositions; analyzed smelting methods, including directional crystallization that provides a natural compositional structure; evaluated mechanical properties at room and high temperatures and oxidation resistance; studied structural features; and provided information on technological equipment and the possibility of obtaining parts by various methods. It is shown that, depending on the composition of the selected matrix, the operating temperature of heat-resistant alloys can increase to 1300-1500°C, which is significantly higher than the existing operating temperatures for nickel heat-resistant alloys. We conclude that the studied materials are promising for use in aircraft engine manufacture and the aerospace industry.