Diretrizes da Federação Mundial das Sociedades de Psiquiatria Biológica para o tratamento biológico da esquizofrenia. Parte 2: tratamento de longo prazo

Falkai, Peter; Wobrock, Thomas; Lieberman, Jeffrey A.; Glenthøj, Birte; Gattaz, Wagner F.; Möller, Hans‐Jürgen

doi:10.1590/s0101-60832006000700004

Cited by 3 publications

(3 citation statements)

References 127 publications

(175 reference statements)

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“…The costs of atypical medications, however, are much higher than the typical ones, with a limited number of second generation antipsychotics. In addition, patients must be within the program criteria, which includes not showing improvement with conventional treatment, the need for a medicalpsychiatric report based on the assessment of psychological impairment made by the BPRS-A; for maintenance of treatment, an improvement of at least 30% after 3 months of treatment so that there is a substitution for atypical medication (4,29) .…”

Section: Discussionmentioning

confidence: 99%

“…However, there is a loss in this effect, when associated with a typical, a fact identified in clinical practices. Moreover, the association of two or more antipsychotics can cause cardiotoxicity by increasing the QT interval (electrocardiographic parameter that represents the electrical systole duration) (28)(29)(30) . These findings may suggest that patients may be at greater risk of developing cardiotoxicity, as 24 patients are associated with more than one type of typical and atypical antipsychotic, and 8 use deposit medication, typical and atypical.…”

Section: Discussionmentioning

confidence: 99%

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Factors related to psychological impairment and quality of life in patients with schizophrenia

et al. 2021

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Objective: to describe the factors related to psychological impairment and quality of life (QoL) of patients with schizophrenia. Method: a cross-sectional, descriptive and correlational study, carried out with 119 schizophrenics. A questionnaire of sociodemographic and clinical variables was applied, plus BPRS-A and QLS-BR scales. Chi-square test and Spearman’s correlation were used, Results: seventy-seven were male and 44 were using typical medications. The “Number of times they were hospitalized” related to “Time of illness” that patients live with schizophrenia showed significance (p=0.266); 91.7% had a severe occupational level (n=109); 34.5% (n=41) had moderate impairment. Conclusion: the greater the degree of psychological impairment, the worse the QoL, this worsening may be related to several factors, as well as disease symptoms.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Factors related to psychological impairment and quality of life in patients with schizophrenia

et al. 2021

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“…Long term treatment is indicated for all patients with schizophrenia 1 . Antipsychotic drugs can be of great benefit for a wide range of psychotic disorders, although treatment can be associated with potential and unpleasant adverse effects 2 .…”

Section: Introductionmentioning

confidence: 99%

A acurácia da Escala de Experiência Sexual do Arizona (ASEX) para identificar disfunção sexual em pacientes do espectro da esquizofrenia

Nunes¹,

Dieckmann²,

Lacaz³

et al. 2009

Rev. psiquiatr. clín.

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Background: Sexual dysfunction is frequent in patients with schizophrenia, it is reported as one of the most distressing antipsychotic's adverse effects and it is directly related to treatment compliance. Objectives: a) to evaluate the accuracy of the Arizona Sexual Experience Scale (ASEX) to identify sexual dysfunction; b) to assess the frequency of sexual dysfunction in a sample of outpatients with schizophrenia and schizoaffective disorder under antipsychotic therapy; and c) to investigate the effect of different antipsychotics on sexual function. Method: Outpatients with schizophrenia or schizoaffective disorder were asked to fulfill both the ASEX and the Dickson Glazer Scale for the Assessment of Sexual Functioning Inventory (DGSFi) at a single interview. Results: 137 patients were interwied. The sensitivity and specificity of the ASEX in relation to DGSFi were: 80.8%, (95% CI = 70.0%-88.5%) and 88.1% (95% CI = 76.5%-94.7%), and the misclassification rate was 9.5%. The ROC curve comparing the ASEX and the DGSFi scores revealed a value of 0.93 (CI = 0.879-0.970), with the optimum cut-off point of ASEX being 14/15. Sexual dysfunction measured was higher in females (79.2%) than in males (33.3%) (χ 2 = 27.41, d.f. = 1, p < 0.001). Discussion: Patients under antipsychotic treatment showed a high level of sexual complaints, and the ASEX proved to be an accurate instrument to identify sexual dysfunction in an outpatient sample of patients with schizophrenia spectrum. Females showed a higher frequency of sexual dysfunctions and sexual drive and ability to reach orgasm were the most affected areas. The use of antipsychotics, especially the combinations, was more likely to impair sexual functioning.

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Kundalini yoga como uma terapia complementar para o Transtorno Obsessivo-Compulsivo

Vaz,

Avila,

Nascimento

et al. 2024

Revista Científica Multidisciplinar Núcleo do Conhecimento

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A definição do Transtorno Obsessivo-Compulsivo (TOC) indica um espectro que se caracteriza por pensamentos obsessivos (obsessões) e por comportamentos repetitivos ou atos mentais (compulsões). As principais alternativas de tratamento são as farmacológicas e as psicoterápicas, no entanto, estima-se que aproximadamente 40 a 60% dos pacientes não atinjam alívio satisfatório dos sintomas. Desta forma, apresentamos o Kundalini Yoga, como um tratamento complementar. Foram realizadas 36 sessões com um protocolo de técnicas “específicas para o TOC”. Foram utilizados para avaliação os seguintes instrumentos: as Escalas Obsessivo-Compulsivo (YBOCS) e dimensional (DYBOCS), os inventários Beck de Ansiedade (BAI), e o Teste de Qualidade de Vida da OMS (WHOQOL). Nesta pesquisa com 24 pacientes adultos, houve uma melhora significativa (46%) na gravidade do TOC, especialmente nos sintomas de conteúdo sexual/religioso (54%) e de contaminação (33%). Também melhoraram em quase 48% os sintomas de ansiedade e todos os aspectos da qualidade de vida (física 9,7%, psicológica 11,7%, social 12,6% e ambiental 4,8%). O Kundalini Yoga se mostrou uma ferramenta efetiva para aliviar os sintomas do TOC em algumas dimensões, reduzir a ansiedade e melhorar a qualidade de vida.

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Diretrizes da Federação Mundial das Sociedades de Psiquiatria Biológica para o tratamento biológico da esquizofrenia. Parte 2: tratamento de longo prazo

Cited by 3 publications

References 127 publications

Factors related to psychological impairment and quality of life in patients with schizophrenia

Factors related to psychological impairment and quality of life in patients with schizophrenia

A acurácia da Escala de Experiência Sexual do Arizona (ASEX) para identificar disfunção sexual em pacientes do espectro da esquizofrenia

Kundalini yoga como uma terapia complementar para o Transtorno Obsessivo-Compulsivo

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